UNACCEPTABLE Presentation on nutrient-dependent pheromone-controlled ecological adaptations

‘The AChemS Program Committee recently completed its initial review of abstracts submitted for the upcoming Annual Meeting. During this review, it was determined that the abstract #319 (see below) is UNACCEPTABLE in its form and therefore I regret to inform you that it has been rejected for inclusion in the Annual Meeting. The reason for this finding, with which I concur, is that the abstract did not follow the guidelines presented in the Call for Abstracts, including the requirement for abstracts to contain methods, results and conclusions. Additionally, it was unclear if any original research was to be presented.

If you have any questions, please do not hesitate to contact me.”

My comment: I’m not going to question this decision on my unacceptable presentation, which clearly prevents the dissemination of integrated information from research that has been presented since 1992 and published during the past 18 years.  For those who are not familiar with what would have happened if abstract 319 was acceptable, I would have been allowed to present this information on a 4ft x 6ft poster board, like I did in my presentation at the Society for Behavioral Neuroendocrinology annual meeting last year. Instead, the concept of ecological adaptations may not become known to olfactory researchers until someone else is provided with 24 square feet of space at a conference for research on chemosensory perception because abstract 319 is unacceptable.

Nutrient-dependent pheromone-controlled ecological adaptations
James V. Kohl. Independent Researcher, Epworth, GA, United States
Chemical ecology drives adaptations via niche construction. Nutrients metabolize to pheromones that epigenetically effect hormones that affect behavior. The epigenetic effects of olfactory/pheromonal input on invertebrate behavior and vertebrate behavior are hormone-organized and hormone-activated. For example: glucose and pheromones alter the secretion of hormones that affect behavior. Systems biology: This model represents the conservation of bottom-up organization and top-down activation via the 1) thermodynamics of nutrient stress-induced and social stress-induced intercellular changes in the microRNA / messenger RNA (miRNA/mRNA) balance; 2) intramolecular changes in DNA via alternative splicings; 3) non-random experience-dependent stochastic de novo gene creation exemplified by the biosynthesis of receptors; 4) the required gene-cell-tissue-organ-organ system pathway that links sensory input directly to gene activation in neurosecretory cells and to miRNA-facilitated learning and memory in the ecologically adapted mammalian brain; and 5) the reciprocity that links the thermodynamics of gene expression to behavior and altered organism-level thermoregulation in species from microbes to man. Examples of nutrient-dependent amino acid substitutions clarify the involvement of seemingly futile thermodynamic control of intercellular and intramolecular interactions, which result in de novo creation of olfactory receptor genes. Thermodynamically controlled cycles of RNA transcription and protein degradation are responsible for organism-level changes in pheromone production, which enable accelerated changes in the nutrient-dependent miRNA/mRNA balance and thermoregulation of ecological adaptations controlled by the physiology of reproduction.FUNDING ACKNOWLEDGMENTS: NoneFCOI DECLARATIONS: JVK is the founder of Pheromones.com

Author: James Kohl

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