There is no such thing as a self-splicing ribozyme. Splicing is energy-dependent. The energy from sunlight is required to Create the enzymes that metabolize food and to link the metabolism of food to the physiology of pheromone-controlled reproduction in species from microbes to humans.
In all species, across all kingdoms, gene expression is energy-dependent and microRNA-mediated. Alternative splicings of RNA link biophysically constrained viral latency from the Creation of sunlight to healthy longevity
“The synthesis of RNA in isolated thymus nuclei is ATP dependent.”
See also:
Trans-kingdom RNA interactions drive the evolutionary arms race between hosts and pathogens 8/28/19
Small RNAs – Big Players in Plant-Microbe Interactions 8/14/19
Trans-Kingdom RNA Silencing in Plant-Fungal Pathogen Interactions 2/5/18
Virus-mediated archaeal hecatomb in the deep seafloor 10/12/16
Eukaryotic plankton diversity in the sunlit ocean 5/22/15
Small RNAs: a new paradigm in plant-microbe interactions (2014)
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.
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