Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia 2/11/20
…new coronavirus (2019-nCoV) infected pneumonia, namely severe acute respiratory infection (SARI) has caused global concern and emergency.
We hypothize that Vitamin C infusion can help improve the prognosis of patients with SARI.
On 2/11/20 These were two of more than 60 additions to indexed published works that attest to the facts about microRNA-mediated prevention and/or control of the new coronavirus crisis from Wuhan and biophysically constrained cancers.
Dietary Restriction and Epigenetics: Part I 12/2/19
Given that numerous age-associated diseases are often polygenic and affect individuals differently, it is possible that they are confounded by interactions between environmental influences and the genome, a process termed ‘epigenetics’.
Epigenetic Regulation by Dietary Restriction: Part II 12/2/19
In the second part of the review, we summarize recent findings that highlight the epigenomic axis of DR, which provides a better understanding of the mechanisms by which its numerous health benefits are achieved.
Vitamin C and Vitamin D were linked to the prevention of all virus-driven pathology in the mouse-to-human model of ecological adaptations via EDAR V370A in: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18
See: The Interplay Between Viral-Derived miRNAs and Host Immunity During Infection
…we offer insights into the underexplored role of viral miRNAs as potential targets for developing therapeutics for treating complex viral diseases.
For comparison, on Darwin Day 2020, I hope that others will ask: “What have neo-Darwinian theorists and Big Bang cosmologists done to help prevent any form of pathology?”
Nutrient stress and/or social stress have been linked to all virus-driven pathology by articles like this one:
See for comparison:
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
Nutrient stress and social stress have been linked to inhibited ATP-dependent RNA synthesis, autophagy, and diseases.
See: MiR-129-3p favors intracellular BCG survival in RAW264.7 cells by inhibiting autophagy via Atg4b
…these data suggested that miR-129-3p could favor MTB survival by inhibiting autophagy via Atg4b.
Conflict of interest: I own the domains Autophagy.pro, microRNA.pro, and RNA-mediated.com
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.