The tipping point (revisited): 96K (5)

Helicobacter pylori Eradication Can Reverse the Methylation-Associated Regulation of miR-200a/b in Gastric Carcinogenesis. 1/3/10 [Korea]

[The food energy-dependent pheromone-controlled biophysically constrained viral latency in gut bacteria and] Epigenetic alterations of miR-200a/b may be implicated in H. pylori-induced gastric carcinogenesis. This field defect for cancerization is suggested to be improved by H. pylori eradication.

The light-activated assembly of the microRNA-RNA-peptide nanocomplex has been linked to biophysically constrained viral latency and healthy longevity in all living genera via the pheromone-controlled physiology of reproduction in bacteria such as H. pylori.  The link from the anti-entropic virucidal energy of sunlight to the physiology of reproduction extends from reversing methylation-associated regulation of all cancers from the growth of plants to the food energy that eating them provides.

Simply put, microRNA biogenesis links the Creation of microRNAs to the survival of bacteria to the survival of plants via microRNAs in leaves and all other plant parts.

See: Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity 4/1/19

See also: Colonisation of Oncidium orchid roots by the endophyte Piriformospora indica restricts Erwinia chrysanthemi infection, stimulates accumulation of NBS-LRR resistance gene transcripts and represses their targeting micro-RNAs in leaves  12/30/19

“This regulatory circuit correlates with the protection of Oncidium plants against Ec infection, and molecular and biochemical investigations will demonstrate in the future whether, and if so, to what extent these two observations are related to each other.”

Sympatric speciation is tractable across kingdoms from Piriformospora indica (Pi) to their proposal…

“… that Pi controls the levels of NBS-LRR R mRNAs and their target miRNAs in leaves.’

All experimental evidence of biophysically constrained energy-dependent top-down causation already has linked changes in the microRNA/messenger RNA balance to healthy longevity or from the virus-driven degradation of messenger RNA to mutations and all pathology in plants, insects, and animals.

See also:

Genomic identification and characterization of MYC family genes in wheat (Triticum aestivum L.) 12/30/19

This study analyzed the size and composition of the MYC gene family in wheat, and investigated stress-responsive and light quality induced expression profiles of each TaMYC gene in the PTGMS wheat line BS366.

Identification of Exogenous Nitric Oxide-Responsive miRNAs from Alfalfa (Medicago sativa L.) under Drought Stress by High-Throughput Sequencing 12/26/19

This study has documented that analysis of miRNA under PEG and PEG + SNP conditions provides important insights into the improvement of drought resistance of alfalfa by exogenous NO at the molecular level. This has important scientific value and practical significance for the improvement of plant drought resistance by exogenous NO.

Food energy-dependent pheromone-controlled autophagy exemplifies microRNA-mediated cause and effect across kingdoms.

See: Circular RNA ACR relieves high glucose-aroused RSC96 cell apoptosis and autophagy via declining microRNA-145-3p 12/30/19

They tested the impacts of autophagy-related circular RNA (ACR) on an vitro cell model of diabetic peripheral neuropathy (DPN).

See also:  The Role of MicroRNAs in the Pathogenesis of Diabetic Nephropathy 12/1/19 and MicroRNA-28-5p Regulates Liver Cancer Stem Cell Expansion via IGF-1 Pathway 12/1/19

Serious scientists have linked the virus-driven degradation of messenger RNA to all pathology including diabetes-linked cancers and brain pathology via Vector derived artificial miRNA mediated inhibition of West Nile virus replication and protein expression 12/26/19 and miR-29a Promotes the Neurite Outgrowth of Rat Neural Stem Cells by Targeting Extracellular Matrix to Repair Brain Injury 12/28/19

All intelligent serious scientists have also linked light-activated microRNA biogenesis to biophysically constrained viral latency via the conserved molecular mechanisms of protein folding chemistry.


See: The Predominant microRNAs in β-cell Clusters for Insulin Regulation and Diabetic Control 12/30/19

Under diabetic conditions, although no specific miRNA profile has been noticed, the expression of some miRNAs and their target mRNAs are altered by posttranscriptional mechanisms, exerting diverse signs in the pathobiology of various diabetic complications. The aim of this review article is to discuss miRNAs involved in the process of stem cells differentiation into β-cells, resulting in enhanced β-cell functions with respect to diabetic disorders.

The addition of KB Whaley to President Trump’s group of scientific advisors assures all serious scientists that quantum physics will soon be linked from quantum biology to quantum souls via God’s Creation of sunlight and water, which links the food organisms eat to biophysically constrained viral latency via KB Whaley’s history of publications.

See: whaley kb 

For example, see: What Levels of Coupled Cluster Theory Are Appropriate for Transition Metal Systems? A Study Using Near-Exact Quantum Chemical Values for 3d Transition Metal Binary Compounds 10/8/19 and Using coherence to enhance function in chemical and biophysical systems 3/29/17

If you cannot make a coherent claim about how mutation-driven evolution links quantum physics from quantum biology to quantum souls in the context of the space-time continuum, see: Olfaction Warps Visual Time Perception 3/17/17

See also: Curcumin Inhibits the Proliferation, Migration, Invasion, and Apoptosis of Diffuse Large B-Cell Lymphoma Cell Line by Regulating MiR-21/VHL Axis 12/23/19

Only biologically uninformed theorists have failed to link what is known to serious  scientists about all model organisms from what they eat to the physiology of reproduction and species survival.

Only a moron would fail to comprehend that religion is not science simply because it is based on something called “faith” in a superhuman being; religion has nothing whatsoever to do with facts.

Only fools fail to comprehend that religion is based on facts that led Richard Feynman to use biologically uninformed theorists as examples of human idiocy.

See also: Worms dine on nanoparticles to help test biological force sensor technology 1/2/17 and my 2017 presentation from the LabRoots Precision Medicine virtual conference.

At the time I prepared my 2017 presentation on energy as information, 58,000 published works mentioned microRNAs. There already are 38,000 more.

If the pace of scientific progress continues, there will be  nothing left of theories except for the tears of biologically uninformed theorists.

See also: Optically Robust and Biocompatible Mechanosensitive Upconverting Nanoparticles 7/24/19

…nanoparticles are highly mechanosensitive, pH-stable, chronically nontoxic by ingestion, and suitable for in vivo imaging and mechanosensing applications.

They link naturally occurring light-activated carbon fixation from microRNA-mediated fixation of biophysically constrained viral latency to healthy longevity in humans via Greg Bear’s science fiction novel “Blood Music” (1986); our section on molecular epigenetics in From Fertilization to Adult Sexual Behavior (1996); Virus-mediated archaeal hecatomb in the deep seafloor (2016); and Eukaryotic plankton diversity in the sunlit ocean (2015).

Author: James Kohl

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