The tipping point (revisited): 94K (1)

microRNA Items: 1 to 94059

More than 94,000 indexed published work attest to the fact that the light-activated assembly of the microRNA-RNA-peptide nanocomplex links the physiology of reproduction to biophysically constrained viral latency and healthy longevity in all living genera.

It has become perfectly clear that energy-dependent changes in Every base matters: [see] assessing small subunit rRNA primers for marine microbiomes with mock communities, time series and global field samples (8/14/15) All changes in all bases are energy-dependent. The Creation of the energy-as-information that causes the light-activated and/or temperature-dependent changes in thermodynamic cycles of protein biosynthesis and degradation is biophysically constrained by the physiology of reproduction across kingdoms.

See: Global Trends in Marine Plankton Diversity across Kingdoms of Life 11/14/19

Here we investigate the latitudinal gradients and global predictors of plankton diversity across archaea, bacteria, eukaryotes, and major virus clades using both molecular and imaging data from Tara Oceans. We show a decline of diversity for most planktonic groups toward the poles, mainly driven by decreasing ocean temperatures. Projections into the future suggest…

Reported as: Plankton Biodiversity Mapped Globally 11/14/19

“We found that temperature was the largest determinant of these diversity patterns, so the higher [the] temperature, the higher [the] diversity,” Bowler said. “But it’s not only temperature. It’s also productivity of different regions, nutrient concentrations, and so on.” Some eukaryotes like diatoms, which get their energy from sunlight, appeared to have higher diversity at cooler temperatures, which might be because they can survive at lower temperatures than cyanobacteria can.

They failed to link God’s Creation of sunlight and water to all energy-dependent oxygen-dependent ecological adaptations on Earth via the temperature-dependent and nutrient-dependent pheromone-controlled physiology of reproduction in species from microbes to mammals.

See for comparison: Eukaryotic plankton diversity in the sunlit ocean 5/22/15

Diversity emerged at all taxonomic levels, both within the groups comprising the ~11,200 cataloged morphospecies of eukaryotic plankton and among twice as many other deep-branching lineages of unappreciated importance in plankton ecology studies. Most eukaryotic plankton biodiversity belonged to heterotrophic protistan groups, particularly those known to be parasites or symbiotic hosts.

Recognizing that the Creation of sunlight is required to change diversity in the sunlit ocean is the first step toward recognizing the difference between mutation-driven evolution and ecological adaptations linked to sympatric speciation.

The fact that virucidal light biophysically constrains diversity during the sympatric speciation the found at all taxonomic levels went missing for ~17 months, but all the facts came back into play in:

Virus-mediated archaeal hecatomb in the deep seafloor 10/12/16

We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.

The archael hecatomb is a term used to indicate the 10% survival rate that characterizes controlled archaeal dynamics. The biophysically constrained dynamics link God’s Creation of virucidal light and God’s Creation of water to the archaeal hecatomb via oxygen-dependent ecological adaptations. The ecological adaptations are RNA-mediated. That fact became an insurmountable problem for biologically uninformed science idiots, who have since been forced to replace the term geobiology with their invented term ‘geovirology’ in an attempt to fool others who know even less about global biogeochemical cycles of energy-dependent protein biosynthesis and degradation.

All serious scientists saw the problem that examples of human idiocy created.

For example, see: Integrated mobile genetic elements in Thaumarchaeota 3/18/19

They claimed that integrated MGE (iMGE)

“…might make important contributions to the fitness and adaptation of their hosts.”

That claim about adaptations in hosts placed first author, Mart Krupovic and senior author, Eugene V. Koonin into untenable positions. The mobile genetic elements were linked to young earth creationism in Spindle-shaped viruses infect marine ammonia-oxidizing thaumarchaea 7/18/19 via the claim that:

…viral predation has a profound impact on thaumarchaeal functioning and mortality, thereby regulating global biogeochemical cycles.

“Global biogeochemical cycles” is the operative phrase that refutes neo-Darwinian pseudoscientific nonsense by starting with Darwin’s “conditions of life.” He repeatedly insisted that others start with his “conditions of life” — almost begging them to not place natural selection first. He knew nothing about viral predation or DNA. But he was more intelligent than those who have learned about the conserved molecular mechanisms that have been linked to energy-dependent sympatric speciation by all serious scientists who have used experimental evidence of top-down causation to advance factual representations of how the virus-driven degradation of messenger RNA has been linked from mutations to all pathology.

Note: I am an emeritus member of the American Society for Clinical Pathology.

In the November 2019 Issue of their flagship journal, you can find: MicroRNA-221 and MicroRNA-222 in Common Human Cancers: Expression, Function, and Triggering of Tumor Progression as a Key Modulator 10/10/19

In this review, we have highlighted the most consistently reported dysregulated miRNAs that trigger human tissues to express cancerous features and surveyed the role of those miRNAs in metastasis, apoptosis, angiogenesis, and tumor prognosis. Also, we applied the causes of drug resistance and the role of coordinated actions of these miRNAs to epigenetic changes and selected miRNAs as a potential type of cancer treatment.

The fact that researchers from Iran have indirectly linked viral predation to the mircroRNA-mediated regulatation of light-activated biophysically constrained global biogeochemical cycles and thermodynamic cycles of protein biosynthesis and degradationis a neo-Darwinian evolutionary theory killer. That fact also removes theories about Big Bang cosmology from any further consideration whatsoever.

No experimental evidence of top-down causation starts with the emergence of energy and nothing links anything except energy-as-information to biophysically constrained viral latency and healthy longevity.

Thus, the invention of the term ‘geovirology’ will be a subject for ridicule.

See: Geobiology vs geovirology (in prep).

But first, see:

And for comparison, see:



Author: James Kohl

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