The microRNA-mediated future of humanity (9)

Constrained entropy starts with the Creation of hydrogen

Thanks to Nyan Prater II for linking “captured chaos” from energy-dependent changes in subatomic particles and “atoms to ecosystems” at every level of investigation from “angstroms to ecosystems.”

Others recently reported that their models of biophysically constrained viral latency were flawed. Perhaps now, they will support our President by starting with God’s Creation of anti-entropic UV light and water.

See: Embedded model discrepancy: A case study of Zika modeling  (5/4/20)

If intelligent people do not support President Donald J. Trump, all of us may watch as coronavirus pathology adapts to become more like Ebola virus pathology.

See: Mysterious Coronavirus Illness Claims 3 Children in New York 5/9/20

In the context of adaptations in viruses that increase their virulance, I posted this diagram from Nyan Prater II to my FB page  last year

Constrained entropy starts with the Creation of hydrogen

with this comment:

This generalized understanding is missing from presentations during the Genetics & Genomics 2019 virtual conference. Indeed, there may be no mention at all of the need to link the creation of energy to all biodiversity via biophysically constrained viral latency.

Nyan Prater II replied:

Yeah, it’s a helpful tool that is missing from all public textbooks due to the proliferation of nuclear weapons in the late 1930’s and early 1940’s. Hope it helps you in your quest to find the cure for malignant tumors (cancer) and the like.

It did. Also, President Trump’s scientific advisor, KB Whaley and others have since linked quantum coherence to coherently organized biology via Nyan Prater II’s diagram. At their level of understanding of the energy in hydrogen atoms, the energy-dependent endogenous substrates of all cell types can be linked to protection of all organized genome from virus-driven chaos, which has been linked from coronavirus pathology and all other pathology to cancers and neurodegenerative diseases.

You may not need to understand any of this. If, however, you choose to believe in theoretical pseudoscientific nonsense touted by neo-Darwinian theorists and Big Bang cosmologists, you are probably going to suffer unnecessarily and die prematurely. Thus, it is important to remember that God did not cause the unnecessary suffering and premature deaths.

Theorists did! For more information on top-down energy-dependent causation and constraints on effects see the mouse-to-human model of food energy-dependent microRNA-mediated biophysically constrained endogenous retroviruses via EDAR V370. It was published in 2018 as Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18

Researchers recently rediscovered a nutrient-dependent epigenetic variant that links vitamin C to what is probably a glucose and glucose dehydrogenase-dependent base pair change. The base pair change results in addition of a methyl group to a cytosine base, which takes on a hydroxyl group to form different 5-hydroxymethylcytosines (5hmCs). Different 5hmCs are associated with differences in cell types that have the same genetic backgrounds. Nutrient-dependent epigenetically-marked bases help to explain how hundreds of cell types in the human body and in the brain [20] are differentiated and how they maintain their glucose-dependent and other nutrient-dependent receptor-mediated identities [21].

For example, calcitriol is the active form of vitamin D. Its effects on the microRNA(miRNA)/messenger RNA (mRNA) balance appear to protect against virus-driven energy theft linked from perturbed protein folding to colorectal cancer. MiRNA-627 targets the mRNA that encodes an enzyme linked to histone demethylation and amino acid substitutions that increase stability of hydrogen bonds in DNA, which are important to protein folding [22].

See for comparison (from exactly 2 years later): Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections  4/18/20

…we recommend supplementation above the RDA for vitamins C and D. As noted above, recent meta-analyses concluded significant reductions in the risk and impact of both upper and lower respiratory tract infections such as the common cold and pneumonia, including disease severity and risk of death in older patients, with vitamin C supplementation [27,28,79].

Reported as: Vitamins C, D can help prevent COVID-19 4/23/20

Because people are simply not getting enough of these vital nutrients through their diets, researchers are urging people to not only a take a daily multivitamin but doses of 200 milligrams or more of vitamin C — higher than the suggested federal guidelines of 75 milligrams for men and 50 for women — and 2,000 international units of vitamin D.

See also: What is life when it is not protected from virus driven entropy 3/30/16 (Video 6:37 minutes long)

The difference between my detailed model of how God’s Creation of sunlight and water compared to the simple-minded claims about vitamin C and vitamin D have been linked from light-activated changes in the microRNA/messenger RNA balance and healthy longevity across kingdoms via the physiology of reproduction is in the levels of complexity that must be accounted for.

See the comments on the model from the presentation above:

If I recall correctly the protein that creates a thin layer around human babies in the womb is made from a virus that was absorbed and turned to use by mammals a very long time ago.
If you knew more about logic you wouldn’t be hurling ad hominems over and over. You would disprove it. But when at a loss for what to do, you hurl and scream. Not science.

Cooperative Orthogonal Macromolecular Assemblies with Broad Spectrum Antiviral Activity, High Selectivity, and Resistance Mitigation This was published on 4 April 2016, which is one reason why it was not included in my accurate representation of what is known about the detailed energy-dependent links from angstroms to ecosystems in all living genera. It also appears to indirectly address facts about the difficulty of conveying what is known to serious scientists when they try to address an audience of laypersons. The article about the “Cooperative Orthogonal Macromolecular Assemblies,” which appears to prevent virus-driven energy theft and all mutation-driven pathology was reported as “One macromolecule to rule them all, from Ebola to Zika and the flu

“This is the first time that viruses have been shown to have such a strong impact on adaptation.”

Viruses revealed to be a major driver of human evolution July 13, 2016 

Herman and his colleagues have effectively integrated all of the earlier ideas into a unified theory for energy and the evolution of human characteristics.
They did not! They made a feeble attempt to establish the claims of pseudoscientists by including the role of energy, which everyone knows is required. But they made no claim about how virus-driven energy theft is prevented, which all serious scientists know is also required to link energy-dependent changes from angstroms to ecosystems in all living genera.
Olfactory organ of Octopus vulgaris: morphology, plasticity, turnover and sensory characterization (2016) Anna Di Cosmo’s group has consistently stayed ahead of most, if not all others, by linking physics and chemistry to the conserved molecular mechanisms of biophysically constrained protein folding chemistry in marine invertebrates to terrestrial vertebrates. The link is to an open access pre-print.
These two articles link nutrient energy-dependent hydrogen-atom transfer in DNA base pairs in solution from microRNA flanking sequences to the immune system and the physiology of reproduction in species from microbes to humans via RNA-mediated amino acid substitutions in the context of biophysically constrained protein folding biochemistry. Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees (2003) MicroRNA-Driven Developmental Remodeling in the Brain Distinguishes Humans from Other Primates (2011)
Transcriptomics resources of human tissues and organs about energy or microRNAs is included in this report. It is fascinating because of what it lacks. Simply put, it has no explanatory power.
See also: Predicting miRNA Targets by Integrating Gene Regulatory Knowledge with Expression Profiles There is too much information available that links energy-dependent hydrogen-atom transfer in DNA base pairs in solution and nutrient dependent microRNA flanking sequences from RNA-mediated amino acid substitutions to cell type differentiation in all living genera via the physiology of reproduction. Each time I see the available information ignored, I wonder whether it’s ignorance or the fear that the ignorance about energy-dependent cell type differentiation will be revealed.
Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan Excerpt: “The signal we observe is driven by rs429358, a non-synonymous Cys112Arg variant, which defines the ε4 allele and which has not previously been shown to be the causal variant influencing lifespan.” My comment: Their causal variant, like all other causal variants, is a nutrient-dependent RNA-mediated amino acid substitution. It links energy-dependent metabolic networks and genetic networks to the physiology of reproduction. Metabolic networks and genetic networks link supercoiled DNA to protection of organized genomes from virus-driven entropy.
See also: McGovern Institute awards prize to neurogeneticist Cori Bargmann Excerpt: “…on Wednesday March 30, 2016. At 4.00 pm she will deliver a lecture entitled “Genes, neurons, circuits and behavior: an integrated approach in a compact brain…” My comment: An integrated approach must include what is known about virus-driven energy theft and entropy. If it does not, the Zika virus is less likely to be linked from perturbed RNA-mediated protein folding chemistry to craniofacial morphology and brain development. An important aspect of nutrient-dependent transgenerational epigenetic inheritance of morphological and behavioral phenotypes may be missed. Nutrient-dependent RNA-mediated DNA repair is the most likely missing link that explains morphological and behavioral diversity in C. elegans compared to P. pacificus, a predatory nematode with teeth.

Microbiologists should be trained to understand food energy-dependent pheromone-controlled biologically-based cause-and-effect in species from microbes to humans. If they do not understand how to link the potential of hydrogen from thermodynamic cycles of protein folding chemistry to cause-and-effect they should stop working as microbiologists.

The potential of hydrogen is referred to as pH. Nyan Prater II and President Trump’s scientific advisor, KB Whaley have linked pH to controlled virus-driven chaos in the human body via what is known about how to build a hydrogen bomb.

Think of it like this: Each of us has the equivalent of many hydrogen bombs in our cell types. The food energy-dependent bombs help to protect us against viruses, like Covid-19. If you are not afraid of suddenly exploding (except when you eat too much food), why are you afraid of any virus that causes symptoms of the common cold or influenza?

Remember, since 2007 CDC researchers have known that: “A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission

CDC’s Timothy J. Cunningham disappeared and was found dead 2 years ago. That fact may make me a “walking dead man” but not because I’m going to spontaneously explode like a pot filled with “Miracle Grow.” And I’m not going anywhere near the creek anytime soon. I protected my Angel Trumpets from the frost again last night, and will continue to try to help others to protect themselves from biologically uninformed theorists and Governor Kemp.

Nyan Prater II (wrote) I didn’t know pH = potential of hydrogen. Thank you for educating me on this.

Others won’t admit that it links the facts from your diagram to biophysically constrained human endogenous retroviruses across kingdoms. Only one person ever asked me: “Where does the energy in a hydrogen atom come from?” You were the first to use a diagram to explain to me the link from God’s Creation of UV light to biophysically constrained healthy longevity via His Creation of water and how photosynthesis must be linked from oxidative phosphorylation to RNA-dependent RNA-polymerase and RNA interference.

Re: Plandemic/Judy Mikovits

 “Independent fact-checkers at Science Feedback say information in your post is false. To stop the spread of false news, we’ve added a notice to your post.”
 They are not “independent” fact-checkers. If they were, they would add a notice about this to my post. “The End Of Quantum Reality
Quantum coherence has been linked to light-activated microRNA-mediated coherently organized biology and all biodiversity on Earth by KB Whaley, President Trump’s scientific advisor, and by many other intelligent serious scientists.

See also: “The evolutionist thesis has become more stringently unthinkable than ever before.

Check the facts about quantum reality for yourself before you forget to do what Greg Bear did before his published Darwin’s Radio and Darwin’s Children.

See: Sci-fi author Greg Bear tells Jon about the not-so-distant future of technology and helping Homeland Security (2007).

If you know any evolutionary theorist who claims to be helping Homeland Security via the development of vaccines or drugs to treat vaccine-induced pathology, ask them to check with people who actually work in the lab before they kill us all.



Author: James Kohl

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