Alternative splicing vs mutation-driven evolution
Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology

The memory of oxygen (1)

James V. Kohl @microRNApro 10/22/19 How many times have you claimed that alternative splicings of RNA do not make changes to DNA during the time…

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Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Diseases & Disorders Ecology

Patented Creation vs Evolution of Disease (6)

The Nobel Prize in Physics 2018 was awarded to researchers whose inventions revolutionized laser physics. Femtosecond blasts of ultraviolet light have been linked from RNA-mediated…

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Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Diseases & Disorders Ecology RNA interference Scientific Discoveries What's in the News

Light-activated chemogenetic kinetics (1)

Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects 8/14/19 …hydrophobic interactions may have catalytic roles also in other biological…

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Posted in Adaptations Autophagy Chemogenetics Cytosis Diseases & Disorders Ecology Light Energy Subatomic

Nutrient-dependent Pheromone-controlled cures (1)

See first: Lewis Thomas (revisited): 90K (7) The existence of light-activated inter-organism systems of genetic regulation has been relatively ignored for ~25 more years, which…

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Posted in Adaptations biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology Model Organisms RNA interference RNA-mediated epigenetic regulation of gene expression

Sunlight, hydrophobicity and biodiversity (3)

Ed Yong sneaks up from behind with A New Clue to How Life Originated 8/12/19 A long-standing mystery about early cells has a solution—and it’s…

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Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology RNA-directed DNA methylation Subatomic

Sunlight, hydrophobicity and biodiversity (1)

A five-coordinate Mn(iv) intermediate in biological water oxidation: spectroscopic signature and a pivot mechanism for water binding 11/17/15 …a multi-step process that involves the redox-active…

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Posted in Adaptations base editing biophotonics Chemogenetics Diseases & Disorders Ecology RNA interference Subatomic

The tipping point (revisited): 89K (4)

MicroRNA Items: 1 to 88927 See also:  Oral Sunscreen Provides All-Over Protection Exogenous sources of  vitamin B3 (aka Niacinamide/Nicotinamide) and vitamin C link ingestion of…

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Posted in Adaptations Cytosis Diseases & Disorders Ecology Light Energy

The tipping point (revisited): 86,000 publications

“Darwin had a huge data set and no mechanism—where would he publish today? This is a problem!” — Arturo Casadevall Darwin’s light-activated “conditions of life” are…

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Posted in Adaptations biophotonics Cytosis Diseases & Disorders Ecology Subatomic

Kohl and Francoeur at 25 (4)

Re: Pathological Pseudomonas aeruginosa vs beneficial Pseudomonas fluorescens Pattern recognition for ages 10+ Subatomic and Cytosis Summary: Changes in base pairs biophysically constrain viral latency….

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Posted in Adaptations Diseases & Disorders Ecology MicroRNA biogenesis Model Organisms Pheromones

DS Wilson’s view of biophysically constrained life (3)

A Different Kind of Theory of Everything (2/19/19) 1) In 1964, during a lecture at Cornell University, the physicist Richard Feynman articulated a profound mystery…

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