New imaging techniques have linked The Art of Building Small, from molecular switches to motors (2016 video) and cryo electron microscopy (cryo-EM) from light-activated microRNA biogenesis…
Wang et al (2013) make it clearer that epigenetic modifications of genes found in social chromosomes entered continuum of adaptive evolution before the sex chromosomes.
“… the “mutational vicinity” is probably found in the molecular vicinity of a “metabolic niche”.
I think what they’ve just shown us exemplifies the molecular biology of epigenetically driven adaptive evolution.
I include more information about the molecular mechanisms responsible for “…sex-specific regulation of miRNA levels that are known to influence sexually dimorphism of mRNA concentrations in the brains of mice” and in other species from microbes to man.
the logic of gene regulatory networks in adaptive evolution does not skip any species.
control of homeostasis by the epigenetic effects of proper nutrition and social stress inhibition might prevent our diet-driven and social stress-driven extinction.