Tag: social
#SFN2019 to 2012: Hiding the facts (2)
Polycomb repressive complex 1: Regulators of neurogenesis from embryonic to adult stage extends our 1996 claims in From Fertilization to Adult Sexual Behavior to all…
Light-activated continuous environmental tracking (1)
New imaging techniques have linked The Art of Building Small, from molecular switches to motors (2016 video) and cryo electron microscopy (cryo-EM) from light-activated microRNA biogenesis…
Nutrient-dependent / pheromone-controlled social structure
Wang et al (2013) make it clearer that epigenetic modifications of genes found in social chromosomes entered continuum of adaptive evolution before the sex chromosomes.
Epistasis as the primary factor in molecular evolution
“… the “mutational vicinity” is probably found in the molecular vicinity of a “metabolic niche”.
Epigenetic maintenance of transcription / neuronal migration
I think what they’ve just shown us exemplifies the molecular biology of epigenetically driven adaptive evolution.
Epigenetic effects underlie sexual preferences IV
I include more information about the molecular mechanisms responsible for “…sex-specific regulation of miRNA levels that are known to influence sexually dimorphism of mRNA concentrations in the brains of mice” and in other species from microbes to man.
MicroRNA binds messenger RNA: Adaptive Evolution
This model of systems biology represents the conservation of bottom-up organization and top-down activation and the required reciprocity that links genes to behavior and back.
Sex differences in Alzheimer’s and everything else
the logic of gene regulatory networks in adaptive evolution does not skip any species.
The logic of gene regulatory networks
As an alternative, we could continue to approach disorders of behavioral developmentas if nothing were known about epigenetic links between nature and nuture.
The end of random mutations theory
most people should be closer to thinking in terms of adaptive evolution via ecological, social, neurogenic, and socio-cognitive niche construction, which makes sense.
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.