Precision Medicine Initiative

UV light, H2O, and epigenetic effects… (1)

See first: Coherently organized healthy longevity (4) UV light, H2O, and epigenetic effects affect behavior and sympatric speciation Submitted by James V. Kohl on 9/25/20 for presentation during the Epigenetics – From Bench to Clinic session: RNA modifications and epitranscriptomics​​ Moderator Tony Kouzarides Title: UV light, H2O, and epigenetic effects affect behavior and sympatric speciation UV light, H2O, and epigenetic effects… (1)

The tipping point (revisited): 102K (1)

See first:  The tipping point (revisited): 101K (1) 4/22/20 and Vaccines do not control pandemics (1) 5/15/20 Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion 5/11/20 They linked virus-driven changes in light-activated energy-dependent differences in hydrogen-atom transfer in DNA base pairs in solution from microRNA flanking sequences The tipping point (revisited): 102K (1)

Olfaction and microRNA signaling constrain longevity (1)

Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent Olfaction and microRNA signaling constrain longevity (1)

Epic failure of the FDA: Gottlieb resigns (1)

Autophagic cell death restricts chromosomal instability during replicative crisis 1/22/19 Our data suggest that autophagy is an integral component of the tumour suppressive crisis mechanism and that loss of autophagy function is required for the initiation of cancer. Reported as: In surprising reversal, scientists find a cellular process that stops cancer before it starts We Epic failure of the FDA: Gottlieb resigns (1)

Electrons build fractal shapes and prevent lung cancer

Physicists build fractal shape out of electrons Non-integer dimensions, such as 1.58, can be found in fractal structures, such as lungs.   This links the number of decimals in pi from quantum physics to quantum souls via the super symmetry of a circle and the physiology of pheromone-controlled reproduction in bacteria that create differences uranium Electrons build fractal shapes and prevent lung cancer

Quantized energy-dependent viral trophism (3)

Summary: If the pathway is ancestral, how and when did it evolve to protect species from microbes to humans from the virus-driven degradation of their messenger RNA? Peer-Reviewed Science: A “Mathematical Proof of Darwinian Evolution” Is Falsified The theorem addresses only the effects of natural selection. Fisher did not directly address any other effect (mutation, Quantized energy-dependent viral trophism (3)

Energy as information and constrained endogenous RNA interference (4)

Premise: Sunlight is the energy as information that is required to link endogenous RNA interference to healthy longevity Counter claim:  The Quantum Thermodynamics Revolution: Information theory Understanding entropy as a subjective measure allows the universe as a whole to evolve without ever losing information. Precision Medicine virtual conference, Feburary 22-23, 2017 Title: Energy as information Energy as information and constrained endogenous RNA interference (4)

Light-activated feedback loops vs self-organization of ecosystems

John Lieff has been trying to update his ridiculous misrepresentations of biologically-based cause and effect to match the accurate representations we made in a section on molecular epigenetics in our 1996 Hormones and Behavior review. From Fertilization to Adult Sexual Behavior Nothing can stop him, but this will provide the next source for material that Light-activated feedback loops vs self-organization of ecosystems