Tag: pre-mRNA
Posted in Adaptations Alternative Splicings Diseases & Disorders Ecology Human Pheromones microRNA editing
microRNA-mediated sex differences (1)
For recent support of our claims from 23 years ago, see: Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier…
Posted in Adaptations Alternative Splicings base editing Chemogenetics Cytosis Diseases & Disorders Ecology Human Brain
#SFN2019 to 2012: Hiding the facts (1)
From Fertilization to Adult Sexual Behavior (1996) Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to…
Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Diseases & Disorders Ecology RNA interference Scientific Discoveries What's in the News
Light-activated chemogenetic kinetics (1)
Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects 8/14/19 …hydrophobic interactions may have catalytic roles also in other biological…
Posted in Adaptations Alternative Splicings Diseases & Disorders Ecology Human Pheromones Model Organisms Pheromones RNA editing
The tipping point (revisited): 85,000 publications (3)
Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) The synthesis of RNA in…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.