New imaging techniques have linked The Art of Building Small, from molecular switches to motors (2016 video) and cryo electron microscopy (cryo-EM) from light-activated microRNA biogenesis…
Wang et al (2013) make it clearer that epigenetic modifications of genes found in social chromosomes entered continuum of adaptive evolution before the sex chromosomes.
“… the “mutational vicinity” is probably found in the molecular vicinity of a “metabolic niche”.
I think what they’ve just shown us exemplifies the molecular biology of epigenetically driven adaptive evolution.
The authors are among many, who seem to have missed a likely epigenetic link from maternal and/or acquired ferritin deficiency to thyroxine transport, brain development, and behavior.
the logic of gene regulatory networks in adaptive evolution does not skip any species.
The only explanation for adaptive evolution with any across species explanatory power is found in my details of the epigenetic effects of olfactory/pheromonal input on intracellular signaling and stochastic gene expression…