Tag: mRNA stability
The tipping point (revisited): 96K (1)
Happy New Year! Unless you are a biologically uninformed theorist. If so, see first and suffer: The tipping point (revisited): 95K (5) 12/11/2019 On 1/1/2020,…
Dmitri Petrov refutes theistic evolution, again
More than another year has passed, but here is a new attempt to present old information on biophysically constrained viral latency as if the information…
mRNA Structure and Function (1)
See also: THE WORLD’S LARGEST MEETING TO ACCELERATE OLIGONUCLEOTIDE AND PEPTIDE PRODUCTS FROM EARLY DISCOVERY TO LATE-STAGE DEVELOPMENT & COMMERCIALIZATION May 11-20, 2020 The light-activated…
Pheromones biophysically constrain disease (1)
[Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)] (1994) Understanding site-specific phosphorylation of amino acids that differentiate all cell types…
#SFN2019 to 2012: Hiding the facts (7)
Ariel Bazzini linked natural selection for food energy-dependent pheromone-controlled codon optimality to biophysically constrained viral latency via RNA-mediated fixation of amino acid substitutions and sympatric…
Chemogenetic kinetics (7): DHA vs consensus (3)
My tweets made nearly 78,000 impressions on 9/28/19. Moving forward, see: Natural selection shapes variation in genome-wide recombination rate in Drosophila pseudoobscura 9/30/19 … (1)…
Chemogenetic kinetics (6): Plants-Mice-Cattle-Humans
Semen miRNAs Contained in Exosomes as Non-Invasive Biomarkers for Prostate Cancer Diagnosis 9/24/19 This links light-activated microRNA biogenesis in plants from microRNAs in mammalian milk…
Trans-kingdom RNA interactions (3)
Intracellular innate immune surveillance devices in plants and animals 12/2/16 Excerpts: 1) In plants and animals, innate immunity involves both cell surface receptors (1) and…
Sunlight, hydrophobicity and biodiversity (3)
Ed Yong sneaks up from behind with A New Clue to How Life Originated 8/12/19 A long-standing mystery about early cells has a solution—and it’s…
Genetic endemism: apologetics vs epigenetics (2)
Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner (6/26/19) Ariel Bazzini supports claims of nutrient-dependent pheromone-controlled ecological adaptations…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.