Posted in Adaptations Autophagy Chemogenetics Cytosis Diseases & Disorders Ecology MicroRNA biogenesis Model Organisms RNA interference

Chemogenetic kinetics (2): Extinction

Biologically uninformed theorists failed to link light-activated energy-dependent “conditions of life” to biophysically constrained viral latency. That led them to ignore the consequences of virus-driven…

Continue Reading...
Posted in Adaptations Autophagy base editing Chemogenetics Diseases & Disorders Ecology

Chemogenetic kinetics (1): Creation

Summary: The virus-driven theft of the sun’s anti-entropic energy, which is required for biophysically constrained cell type differentiation, causes the degradation of messenger RNA (mRNA)….

Continue Reading...
Posted in Adaptations biophotonics Diseases & Disorders Ecology Light Energy Physics RNA interference

Light and life-sucking black holes (2)

Ethan Siegel may be the first to have responded, without attribution, to my claims in Light and life-sucking black holes (1) See: Could All Our…

Continue Reading...
Posted in Adaptations biophotonics Cytosis Diseases & Disorders Ecology Subatomic

Kohl and Francoeur at 25 (4)

Re: Pathological Pseudomonas aeruginosa vs beneficial Pseudomonas fluorescens Pattern recognition for ages 10+ Subatomic and Cytosis Summary: Changes in base pairs biophysically constrain viral latency….

Continue Reading...
Posted in Adaptations Alternative Splicings Common Scents Thoughts Diseases & Disorders Ecology MicroRNA biogenesis Model Organisms RNA–Mediated Epigenetic Heredity

Non-random vs random selection for receptor clonotypes

High frequency of shared clonotypes in human B cell receptor repertoires Reported as: Decoding the human immune system (2/13/19) The receptors randomly select and join…

Continue Reading...
Posted in Adaptations Autophagy Cytosis Diseases & Disorders Ecology MicroRNA biogenesis Scientific Discoveries Subatomic What's in the News

Viral latency vs deadly paleoanthropology (2)

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target Re: “Virus infection reprogrammed host lipid metabolism” (with my emphasis) Within the major category of metabolism, there…

Continue Reading...
Posted in Autophagy base editing biophotonics Ecology Light Energy MicroRNA biogenesis RNA interference

Energy-dependent thymic involution vs evolution (2)

Summary: The “initiator” RNA links the virus-driven degradation of messenger RNA from constraint-breaking mutations to all pathology via what is known about biophysically constrained viral…

Continue Reading...
Posted in Adaptations Autophagy biophotonics Cytosis Ecology MicroRNA biogenesis Model Organisms RNA-mediated epigenetic regulation of gene expression Subatomic

10,000 reasons to believe in biophysical constraints (3)

See: The Darwin Code by Greg Bear Charles Darwin was wise enough not to pin down what he could not see or know, and so,…

Continue Reading...
Posted in Adaptations Autophagy Cytosis Subatomic

Energy-dependent ‘futile cycles’ of autophagy

Quantized energy from virucidal sunlight protects the cell types of all living genera from the degradation of messenger RNA that links mutations to pathology. That…

Continue Reading...
Posted in Adaptations Alternative Splicings base editing Ecology MicroRNA biogenesis RNA-directed DNA methylation What's in the News

microRNA targeting efficacy refutes ridiculous theories

The biochemical basis of microRNA targeting efficacy Hold on, this is waiting to be approved by BioRxiv. This highly significant somewhat cloaked advancement of a…

Continue Reading...