Tag: microRNA
Biological Function of Autophagy (2)
“How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in…
Biological Function of Autophagy (1)
Autophagy is oxygen-dependent. Oxidative phosphorylation links the Creation of sunlight and water to the ATP-dependent creation of RNA and to biophysically constrained RNA interference, which…
MicroRNAs biophysically constrain Virus-driven pathology (4)
Passive-aggressive antagonist Jon Lieff is again attempting to sneak up from behind on FB via his 11/26/19 regurgitation of this report on Cell signalling breakthrough…
Chemogenetic kinetics (2): Extinction
Biologically uninformed theorists failed to link light-activated energy-dependent “conditions of life” to biophysically constrained viral latency. That led them to ignore the consequences of virus-driven…
Chemogenetic kinetics (1): Creation
Summary: The virus-driven theft of the sun’s anti-entropic energy, which is required for biophysically constrained cell type differentiation, causes the degradation of messenger RNA (mRNA)….
Light and life-sucking black holes (2)
Ethan Siegel may be the first to have responded, without attribution, to my claims in Light and life-sucking black holes (1) See: Could All Our…
Kohl and Francoeur at 25 (4)
Re: Pathological Pseudomonas aeruginosa vs beneficial Pseudomonas fluorescens Pattern recognition for ages 10+ Subatomic and Cytosis Summary: Changes in base pairs biophysically constrain viral latency….
Non-random vs random selection for receptor clonotypes
High frequency of shared clonotypes in human B cell receptor repertoires Reported as: Decoding the human immune system (2/13/19) The receptors randomly select and join…
Viral latency vs deadly paleoanthropology (2)
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target Re: “Virus infection reprogrammed host lipid metabolism” (with my emphasis) Within the major category of metabolism, there…
Energy-dependent thymic involution vs evolution (2)
Summary: The “initiator” RNA links the virus-driven degradation of messenger RNA from constraint-breaking mutations to all pathology via what is known about biophysically constrained viral…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.