Posted in Adaptations Alternative Splicings base editing Cytosis Diseases & Disorders Ecology Light Energy Model Organisms RNA interference Subatomic

The tipping point (revisited): Genetics & Genomics 2019

High-Amylose Maize, Potato, and Butyrylated Starch Modulate Large Intestinal Fermentation, Microbial Composition, and Oncogenic miRNA Expression in Rats Fed A High-Protein Meat Diet (4/30/19) All…

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Posted in Adaptations base editing biophotonics Cytosis Ecology Light Energy Physics Scientific Discoveries Subatomic

Life and light-sucking black holes (1)

From Fertilization to Adult Sexual Behavior (1996) We linked energy-dependent RNA-mediated cell type differentiation to all biodiversity via the physiology of reproduction in the molecular…

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Posted in base editing Cytosis MicroRNA biogenesis Model Organisms Subatomic

Biophysically constrained fast adaptation (3)

Excerpt: “One fascinating aspect of innate self-adjusting mechanisms appears to be a programmed “strategy” for adaptation that corresponds in function to programs that human engineers…

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Posted in Adaptations biophotonics Diseases & Disorders Ecology Light Energy Model Organisms

Science journalism: a threat to humanity (1)

Excerpt: Who has not already linked the creation of subatomic particles to light-activated microRNA biogenesis and all biophysically constrained viral latency via the energy-dependent creation…

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Posted in Adaptations Alternative Splicings Autophagy Cytosis Ecology MicroRNA biogenesis Model Organisms Subatomic

The tipping point (revisited): 81,000 publications (1)

Excerpt: miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression (2018) Conclusion: …our results firmly establish alternative splicing as…

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Posted in Adaptations Alternative Splicings Autophagy Cytosis MicroRNA biogenesis Pheromones RNA interference

MicroRNAs as therapeutic agents

Excerpt: See for comparison: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems (2018) Twitter is blocking my tweets when I include links to this open…

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Posted in Adaptations Autophagy Cytosis MicroRNA RNA interference Subatomic

Happy Veteran’s Day 2018 (2)

Excerpt: “…in most cases, the RNA is an mRNA, carrying a protein coding sequence which is translated by the ribosomal machinery into a covalently attached…

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Posted in Adaptations Alternative Splicings Autophagy Diseases & Disorders Ecology MicroRNA biogenesis Model Organisms RNA interference

CSH perspectives: ignore the viral pandemic

The biochemical basis of microRNA targeting efficacy Posted September 11, 2018 as a bioRxiv preprint by David Bartel’s group. One feature that was not captured…

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