Tag: feedback loops
MicroRNA-mediated enhancer-promoter chemistry
Summary: The claim that loop extrusion and homotypic attraction are two antagonistic fundamental forces that are linked to what enhancer-promoter contacts and chromatin domains physically…
pH, amino acids, and health: Effects of sunlight and well wishes
The Trebek effect: The benefits of well wishes 6/7/19 …offers an important insight into what makes families, friendships and communities thrive. Connectedness and its benefits are not…
Abiogenesis vs microRNA biogenesis (3)
Remember this: Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of…
Kohl and Francoeur at 25 (7)
MicroRNA Items: 1 to 20 of 84999 Feed-forward information and zero-lag synchronization in the sensory thalamocortical circuit are modulated during stimulus perception (3/25/19) …directional and…
Darwin Day 2019 (2) #darwinday2019
See: Darwin Day 2019 (1) #darwinday2019 See also: Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution 2/6/19 My summary:…
Light-activated constrained biodiversity
Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism (2015) A single set of light-activated reactions was linked to the production of…
10,000 reasons to believe in biophysical constraints (2)
If you are going to #SFN2018 #SFN, you may need an update on what is known to all serious scientists. For example, compared to theorists,…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.