Tag: construction
Epistasis as the primary factor in molecular evolution
“… the “mutational vicinity” is probably found in the molecular vicinity of a “metabolic niche”.
Human pheromones and autism spectrum disorders (2)
The epigenetic effects are on interactions among all the other neuronal systems and hormone secretion that interact with the GnRH neuronal system, which is central to all developmental differences in the brain of males and females.
Human pheromones, the social brain and simple math computations
Integrating the chemical ecology of the social brain’s adaptive evolution allows it to be viewed – along with adaptive evolution of the CNS – at four levels of niche construction: 1) ecological, 2) social, 3) neurogenic, and 4) socio-cognitive.
Niche construction: ecological, social, neurogenic, and socio-cognitive
No neurogenic niche does not mean no behavior, and no socio-cognitive niche only means that the unconscious affects of sensory stimuli on hormones and behavior will predominate.
Human pheromones and multi-level selection
The problem with multi-level selection in humans seems likely to be one that is due to ignorance about the role of pheromones in the context of ecological, social, neurogenic, and socio-cognitive niche construction.
A detailed model of physical reality and natural selection (722 words)
My idea is that nutrient chemical-dependent ecological niche construction and pheromone-dependent social niche construction contribute equally to the neurogenic niche construction that is responsible for adaptive evolution, development of the mammalian brain, and construction of our socio-cognitive niche.
Evolution of the nervous system: conserved GnRH
GnRH also links nutrient chemicals and pheromones directly to adaptive evolution via the required ecological, social, neurogenic, and cognitive niche construction evidenced by the apparent design in biology.
Human Pheromones and Comparative Epigenomics
What surprises me is that anyone would dispute the significance of modeling behavioral development across the ecological, social, neurogenic, and cognitive niche construction domains by incorporating the epigenetic effects of nutrient chemicals and pheromones on intracellular signaling and stochastic gene expression.
Aging Is Recorded in Our Genes
— as modeled across the ecological, social and neurogenic niche construction that contribute to the adaptive evolution of our cognitive niche.
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.