Tag: Codon optimality
#SFN2019 to 2012: Hiding the facts (7)
Ariel Bazzini linked natural selection for food energy-dependent pheromone-controlled codon optimality to biophysically constrained viral latency via RNA-mediated fixation of amino acid substitutions and sympatric…
Patented Creation vs Evolution of Disease (5)
The 2019 Nobel Prize in Physics – Tuesday 8 October The 2019 Nobel Prize in Physiology or Medicine was awarded to researchers who linked God’s…
Sunlight, hydrophobicity and biodiversity (3)
Ed Yong sneaks up from behind with A New Clue to How Life Originated 8/12/19 A long-standing mystery about early cells has a solution—and it’s…
Bastardized health care (4)
California festival shooter claimed to be of Iranian and Italian descent 7/30/19 …he invited people to read “Might Is Right,” an 1890 book advocating for…
The tipping point (revisited): HYL1
Despite all the efforts against it, Sci-Hub grew: currently there are > 400,000 visitors daily, reaching more than half a million sometimes. Biologically uniformed theorists…
Light and life-sucking black holes (3)
A universal trend of amino acid gain and loss in protein evolution (2/10/2005) Amino acid composition of proteins varies substantially between taxa and, thus, can…
Olfaction and microRNA signaling constrain longevity (1)
Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics…
Epic failure of the FDA: Gottlieb resigns (2)
Epic failure of the FDA: Gottlieb resigns (1) We didn’t know it was possible for cells to survive crisis; we didn’t know autophagy is involved…
Ecological adaptation vs neo-Darwinian nonsense (4)
Kalevi Kull: Organisms can be proud to have been their own designers Cybernetics and Human Knowing vol 7(1), 2000, pp. 45-55 Due to the role…
Light-activated constrained biodiversity (2)
The food energy-dependent creation of olfactory receptors was addressed in the context of their biophysically constrained losses in: Natural Selection on the Olfactory Receptor Gene…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.