Posted in Adaptations biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology Light Energy Periodic Table Physics RNA interference Subatomic

microRNA-mediated prevention of diseases (1)

Extracellular electron transfer powers flavinylated extracellular reductases in Gram-positive bacteria 12/9/19 The results presented here reveal a family of extracellular reductases that possess a post-translationally…

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Posted in Adaptations Alternative Splicings base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology

The tipping point (revisited): 95K (1)

Today is my 10th year Twitter Anniversary. Since I started my account, the number of indexed published works that link light-activated microRNA biogenesis to the…

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Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology Subatomic What's in the News

The tipping point (revisited): 93K (1)

Historical perspective: Targeted photoredox catalysis in cancer cells 9/23/19 On light irradiation, complex 1 induces NADH depletion, intracellular redox imbalance and immunogenic apoptotic cancer cell…

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Endogenous substrates
Posted in Adaptations Alternative Splicings Autophagy base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology Human Pheromones

Patented Creation vs Evolution of Disease (8)

The 2019 Nobel Prize for Physiology or Medicine for their discoveries of how cells sense and adapt to oxygen availability was shared by Gregg L….

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Posted in Adaptations base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology Light Energy MicroRNA biogenesis RNA interference RNA-mediated epigenetic regulation of gene expression

Patented Creation vs Evolution of Disease (2)

See: Patented Creation vs Evolution of Disease (1) 10/2/19 The light-activated assembly of the microRNA-RNA-peptide nanocomplex (aka the polycomb repressive complex) has been linked to…

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Posted in Adaptations biophotonics Diseases & Disorders Ecology MicroRNA biogenesis RNA interference

Brokered regulatory leverage: Breaking Bad (1)

Summary: Breaking Bad. 2008TV-MA 5 Seasons Crime TV Shows. A high school chemistry teacher dying of cancer teams with a former student to secure his…

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Posted in Adaptations biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology Model Organisms RNA interference RNA-mediated epigenetic regulation of gene expression

Sunlight, hydrophobicity and biodiversity (3)

Ed Yong sneaks up from behind with A New Clue to How Life Originated 8/12/19 A long-standing mystery about early cells has a solution—and it’s…

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Posted in Adaptations base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology

The tipping point (revisited): 90K (1)

Role of miRNAs in tumor and endothelial cell interactions during tumor progression 8/3/19 …during dissemination, tumor cells have to escape from the primary tumor mass,…

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Posted in Adaptations base editing Diseases & Disorders Ecology Light Energy MicroRNA biogenesis RNA interference Variations

Relatable not debatable (1)

Earlier today, I spoke with Charles. His superior use of analogies extended from food energy as information: “It’s like extra cheese on pizza,” to successful…

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Posted in Adaptations base editing biophotonics Cytosis Diseases & Disorders Ecology Subatomic

The tipping point (revisited): Big Data (2)

The tipping point (revisited): Big Data (1) Forthcoming: Range: Why Generalists Triumph in a Specialized World See: The Peculiar Blindness of Experts Some made authoritative…

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