Pheromones biophysically constrain disease (1)

[Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)] (1994)

Understanding site-specific phosphorylation of amino acids that differentiate all cell types in all individuals of all living genera outside the context of definitions is “essential to understand basic and disease biology.” (2019)

Theorists and serious scientists seem to live in different biospheres. Understanding how feedback loops link food odors and pheromones to biophysically constrained viral latency can be placed into the context of what is known about the biophysically constrained biosphere commonly referred to as planet Earth.

Feedback loops link odor and pheromone signaling with reproduction (2005)

Included in that fact are these experimentally established facts.

  1. Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition 7/9/16
  2. Strong anion exchange‐mediated phosphoproteomics reveals extensive human non‐canonical phosphorylation 8/21/19
  3. Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner 6/26/19 (webinar)

All scientifically established facts about mRNA stability link the understanding of feedback loops to refutations of nonsense about “reticulate evolution” in Genomic architecture and introgression shape a butterfly radiation (11/1/19)

We used 20 de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies.

Simply put, the energy-dependent organization of organized genomes attests to the fact that organized genomes do not assemble themselves and the fact that pheromones biophysically constrain oxidative phosphorylation, which limits the virus-driven degradation of messenger RNA. The virus-driven degradation of messenger RNA links mutations to diseases in species from microbes to humans.

See:

From Fertilization to Adult Sexual Behavior (1996)

Human pheromones: integrating neuroendocrinology and ethology (2001)

The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences (2006 + 2007)

Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors 3/15/12

Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13

Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems 4/11/14 (preprint)

It took four more years to publish the preprint, which was an invited review of nutritional epigenetics that was returned without review from the journal “Nutrients.”

See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18

A recent publication from the journal “Nutrients” suggests that biologically unformed science idiots are their target audience.

See: Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration 11/22/19

The effect of diet on the gut microbiota was presciently placed into the context of example of human idiocy, by Richard Feynman.

Clearly, food energy is required to support all ecosystems. The fact that pheromones constrain diseases is based on that fact because food is metabolized to species-specific pheromones in species from microbes to humans.

See also: Ecosystem (for ages 14+)

In Ecosystem, 2 to 6 players draft cards and build a dynamically scoring, personal play area of 20 cards. These 20 cards will be made up of streams and meadows, bears and bees, and maybe even a dragonfly or two. At the end of the game, these cards will score points based on their own unique scoring methods. The player with the most diverse, highest scoring ecosystem will be the winner!

Ecosystem can be taught in a matter of minutes, and played in about 15. Players of all ages will learn the rules quickly, and will be focused on building their own unique, organic strategy during their very first game.

 

Author: James Kohl

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