See: Patented Creation vs Evolution of Disease (1) 10/2/19
The light-activated assembly of the microRNA-RNA-peptide nanocomplex (aka the polycomb repressive complex) has been linked to the prevention and/or effective treatment of all cancers by two different groups of researchers. The first group reported this in their 12/25/18 patent. The second group reported it on 10/3/19.
On 10/2/19 I reported on the patent: Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest 12/25/18
See their “Proof of Concept” The Effect of EGFR Targeting Peptides isolated by us on EGFR Autophosphorylation
The ability of different peptides to inhibit autophosphorylation of EGFR is presented by the decrease of the fluorescent signal (Y axis).
On 10/3/19, their measurements of the fluorescent signal were not reported in the context of MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCER
The measurements of fluorescence (proof of concept) again went missing in: Targeting regulator of mitochondrial cell death delivers anticancer activity
Based on these proof-of-concept studies, researchers then generated a cell-permeable peptidomimetic molecule, or a compound that mimics the inhibitory peptide, to target the complex in vivo for targeted cancer therapy.
Scientific creationists from Israel linked their measurements of fluorescence and ‘proof of concept’ from the creation of biological ice nucleators by 1) Pseudomonas syringae in the air, to the light-activated assembly of the microRNA-RNA-peptide nanocomplex and all biodiversity on Earth via the weekend resurrection of the bacterial flagellum in 2) Pseudomonas fluorescens.
Pseudomonas fluorescens got its name because it exemplifies the ability to trap light. It links ultraviolet (UV) light-activated carbon fixation to biophysically constrained RNA interference via the Creation of virucidal sunlight, which prevents the virus-driven degradation of messenger RNA in the organized genomes of Pseudomonas fluorescens, and many other species.
For comparison to the Creation of virucidal light, biologically uninformed science idiots continue to report that ridiculous claims about evolution are on their side in the context of managing virus-driven infectious diseases.
For example, see the forthcoming presentation: Evolution on our side: Evolutionary thinking for the understanding and management of infectious disease 10/10/19
Michael Boots will be talking about his research at this CEMinar. His research focuses on the ecology/epidemiology and evolution of infectious disease. Parasites and pathogens continue to cause a major burden to human health, cause significant damage in agriculture, and are ubiquitous in nature. The overall aim is to understand the evolution of parasites, of host defense and how infectious organisms spread, persist and affect their host populations. They use a combination of evolutionary theory, experimental host-parasite systems, epidemiological models of wildlife and human tropical disease, and field entomology.
Their general theory and experiments concentrate on the role of ecology in the generation and maintenance of diversity in hosts and parasites, the impact of spatial structure on their evolution, and the implications of tolerance in contrast to resistance to infectious disease. They are increasingly interested in applying their evolutionary theory to the management of human and agricultural disease. In addition, they focus on a number of specific disease systems: Squirrel poxvirus; social networks and TB in badgers; TB in wild boar populations; honeybee varroa mite virus interactions; dengue and emerging tropical viruses; human and avian malaria.
His work on honeybee varroa mite virus interactions recapitulates the claims from Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13
In the honey bee, the outputs of gene regulatory networks stemming from near identical genomes are altered by differing nutritional intakes which can be considered to be alternate trajectories along an epigenetic landscape. Differential nutrition results in different morphologies, different physiologies, different nervous systems and very different behaviors, all arising from different developmental trajectories that end in queen and worker. (Gabor Miklos & Maleszka, 2011, p. 403)
Like all other viruses, the varroa mite virus causes the degradation of messenger RNA (mRNA). The degradation of mRNA forces honeybees to ecologically adapt, if they can find enough nutritional food to support their biophysically constrained pheromone-controlled cell type differentiation.
Without the nutritional food, their pheromone-controlled physiology of reproduction cannot lead from the creation of biological ice nucleators to thermodynamic cycles of protein biosynthesis and degradation that link the creation of the sense of smell in bacteria, such as Pseudomonas fluorescens, to our perception of energy and mass in the context of the space-time continuum — as detailed in:
These findings point to a neuronal network in the right temporal cortex that executes flexible temporal filtering of upstream visual inputs based on olfactory information. Moreover, they collectively indicate that the very process of sensory integration at the stage of object processing twists time perception, hence casting new insights into the neural timing of multisensory events.
Timing is everything in the context of species survival, which requires properly-timed foraging behavior to find the nutrients that are required to link the pheromone-controlled physiology of reproduction to sympatric speciation in species from microbes to humans.
See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model (with the claim about online publication date: “Published online: 23 Jan 2017” and Nutrient-dependent/pheromone-controlled adaptive evolution: a model (6/14/13), which refuted the pseudoscientific nonsense from: Mutation-Driven Evolution, which was published on the same day.
Mutation-driven evolution does not link Pseudomonas syringae in the air to all biodiversity on Earth via the UV light-activated weekend resurrection of the bacterial flagellum in soil bacteria, like Pseudomonas fluorescens.