…our results indicated that miR–24–3p directly targeted HPCA to regulate the neuronal differentiation of SH-SY5Y cells. To the best of our knowledge, this is the first demonstration of miR–24–3p inhibition promoting neuronal differentiation by increasing the expression levels of HPCA. Therefore, our findings suggested that miR–24–3p controlled neuronal differentiation by modulating HPCA expression and implicated the miR–24–3p-mediated regulation of HPCA expression as a potential therapeutic target for neuron development disorders in humans. The findings of the present study are summarized in Fig. 6e.
e The schematic model suggests that the inhibition of miR–24–3p promotes neuronal differentiation by increasing HPCA expression levels in SH-SY5Y cells
If you are disgusted with way scientific creationists from South Korea have linked the Creation of sunlight and water from microRNA biogenesis to the biophysically constrained genesis of all biodiversity, read this instead. (It’s pseudoscientific nonsense, but biologically uninformed science idiots will love it.)
We argue that studies reporting multigenerational epigenetic changes impacting the central nervous system must be interpreted with caution, and provide suggestions for how epigenetic information transfer can be mechanistically disentangled from genetic and environmental influences on brain function.
For evidence of how the failure to link the Creation of sunlight and water has led to the development of theories by biologically uninformed science idiots, see:
(In theory) these temporary tattoos alert you when you’ve had too much sun