1/9/20 Selected additions from my PubMed search for: microRNA
Too many additions link energy-dependent changes in microRNA biogenesis from the virus-driven degradation of messenger RNA to cancer.
See for example:
- GALE Promotes the Proliferation and Migration of Glioblastoma Cells and Is Regulated by miR-let-7i-5p
- Epidemiological evidence for associations between variants in microRNA or biosynthesis genes and lung cancer risk
- microRNA-181 serves as a dual-role regulator in the development of human cancers
- Research progress on the interactions between long non-coding RNAs and microRNAs in human cancer
- Specific Inhibition of Viral MicroRNAs by Carbon Dots-Mediated Delivery of Locked Nucleic Acids for Therapy of Virus-Induced Cancer
My focus will continue to be on disease prevention or effective treatments of virus-driven diseases, which have been linked from Microbiome-Association Studies (MAS) to elimination of the pseudoscientific nonsense touted in Genome-Wide Association Studies (GWAS) by at least three patents for energy-dependent microRNA-mediated RNA interference and the pheromone-controlled physiology of reproduction in species from microbes to humans
…vitamin D/VDR-induced miR-26a/b take protective functions in OLP via both inhibiting apoptosis and impeding inflammatory response in oral keratinocytes.
Insights into the expression patterns of miRNAs in response to BYDV in barley provided here will benefit further studies toward understanding the resistance mechanisms and developing novel strategies against virus infections.
Using miRNA inhibitors and mimics we observed that modulation of let-7e-5p expression affected specifically GLP-1 cellular content and basal release, whereas Gcg gene expression as well as acute GLP-1 secretion and cell proliferation were not affected.
In 2012, at the annual meeting of the Society for Neuroscience, few people knew that enteroendocrine cells existed. Diego Bohoroquez and I shared a few laughs about that. We briefly discussed the fact that the enteroendocrine cells were required to link the metabolism of food from the gut microbiome and Microbiome-Association Studies to every aspect of morphological and behavioral biodiversity in organisms that ate other organisms to successfully reproduce via sympatric speciation.
Reported as Researchers map direct gut-brain connection 1/6/15
It was a leap of faith, said Bohórquez, but it worked. A week after introducing the virus, only cells with neuropods became infected.
“That provides a pathway where rabies can go from the lumen of the gut to the nervous system,” said Rodger Liddle, who is a member of the Duke Institute for Brain Sciences. “It implies you might be able to get rabies by eating rabies. Maybe this is a pathway whereby other viruses could infect the nervous system.”
The new study focused on connections between neuropods and neurons closest to the intestine, but the team is now working to trace the whole path from the gut to brain.
My focus has always been on nutrient-dependent pheromone-controlled epigenetic changes linked from ecological variation to ecological adaptations in species from microbes to humans.
See for instance: Epigenetic alterations of testicular germ cell tumours
Indeed, LH: The link between sex and the sense of smell? was the title of the first presentation I made to a scientific forum in 1992.
These suggest that miR-7 mediates NE’s effect on promoting FSH and LH synthesis in porcine pituitary.
See for disease predictions: Neural Inductive Matrix Completion with Graph Convolutional Networks for miRNA-disease Association Prediction 1/6/20
For disease predictions and prevention across kingdoms, see:
In case you didn’t know, autophagy biophysically constrains viral latency. See Autophagy.pro
The Hippo intracellular signaling pathway plays a pivotal role in cell fate determination.
See for comparison: MicroRNA-mediated healthy longevity (2)
I will list and/or comment on the recent news reports that fail to mention what is known about microRNA-mediated viral latency and/or fail to link it to healthy longevity. Facebook censors have threatened to block me from distributing any information that might limit the income Facebook makes by marketing pseudoscientific nonsense. MicroRNA-mediated healthy longevity (1) and MicroRNA-mediated healthy longevity (2) will attest to their treachery.