First biomarker evidence of DDT-autism link
…they point to androgen receptor binding, a process key to neurodevelopment. A study in rats found DDE inhibits androgen receptor binding, an outcome also seen in a rat model of autism.
These chemicals are transferred across the placenta in concentrations greater than those seen in the mother’s blood.
“Unfortunately, they are still present in the environment and are in our blood and tissues. In pregnant women, they are passed along to the developing fetus. Along with genetic and other environmental factors, our findings suggest that prenatal exposure to the DDT toxin may be a trigger for autism.”
Androgen receptor binding is food energy-dependent and microRNA-mediated. The light-activated food energy-dependent creation of microRNAs typically prevents the degradation of messenger RNA, which all serious scientists have linked from mutations to all pathology. The link from fewer energy-dependent microRNAs to autism is the same as the link from DDT to autism.
See: microRNA autism
See for example: Alterations in the MicroRNA of the Blood of Autism Spectrum Disorder Patients: Effects on Epigenetic Regulation and Potential Biomarkers
See for comparison: DDT autism
See for example: Association of Maternal Insecticide Levels With Autism in Offspring From a National Birth Cohort
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.