All those who have ever fought “For God and Country” have brought us to this point. See my series of blog posts about “The Eternal Significance of MicroRNAs” for details.
See for comparison: Imaging in living cells reveals how ‘junk DNA’ switches on a gene
…attached a separate fluorescent tagging system to the target gene that lights up when the gene is activated and undergoes transcription to produce an intermediary readout of the genetic code, a molecule called RNA. Gregor’s team at Princeton previously developed a method of adding fluorescent tags to RNA as it is being created to obtain a real-time readout of gene expression in fly embryos.
They linked the creation of quantized energy from light-activated endogenous substrates to microRNA-mediated cell type stability via fixation of RNA-mediated amino acid substitutions and reported the facts in the context of enhancers and promoters instead of microRNA biogenesis.
Dynamic interplay between enhancer–promoter topology and gene activity
…we identify three distinct topological conformation states and measure their transition kinetics.
They are obviously aware that the creation of quantized energy must be linked to transition kinetics, which is why they obfuscate that fact with use of terms such as enhancer-promoter topology and gene activity. Anyone who has not already linked the creation of quantized energy as information from microRNA biogenesis to all biophysically constrained biodiversity via the physiology of reproduction has pitted their pseudoscientific nonsense against the facts that will be presented by serious scientists who present during Schrödinger at 75 – The Future of Biology – September 2018.
The pseudosceintists will join the biologically uninformed God-less Communists, who have always been the losers.
See for instance: Nature vs. nurture in human sociality: multi-level genomic analyses of social conformity
Ongoing attempts to keep God out of the “big picture” of how Communists want to engineer social conformity cost Chinese neuroscientist, Rao Yi his visa.
Hear his complaint: A top Chinese brain scientist wonders how he ended up on the U.S. visa blacklist
The U.S. embassy in Beijing does not comment on individual visa cases, a spokesperson wrote in an email to ScienceInsider. “I certainly hope that the U.S. will not go down in history as the country which arbitrarily blocks international cooperation in the natural sciences,” Rao wrote in his email plea to embassy officials.
Personally, I hope that the U.S. will continue to go down in history as the country that blocks the attempts of God-less Communists to aggressively or non-aggressively engineer social conformity. Passive-aggressive behavior is still aggression, and U.S. veterans recognize it in its different forms.
We do not naively believe in “peace at any price,” but The American Legion recognizes the horrendous cost of another Korean War. If the prospects for peace are realistic, those prospects must be fully considered.
What is not negotiable is our stance that the United States always maintain a strong national defense. This is one of the Legion’s four pillars, and the Korean War is Exhibit A as to the wisdom of such a posture.
— National Commander Denise H. Rohan
It is time for all US citizens to learn why the stance the United States has taken is non-negotiable. The stance can be framed in the context of this blog post and compared to this blog post by Kevin Mitchell.
Calibrating scientific skepticism – a wider look at the field of transgenerational epigenetics
My overall conclusion is that there is effectively no evidence for TGEI in humans (contrary to widespread belief) and very little in mammals more generally (with one very specific exception).
See for comparison: Bugs in the program: can pregnancy drugs and smoking disturb molecular reprogramming of the fetal germline, increasing heritable risk for autism and neurodevelopmental disorders?
Watch as biologically uninformed theorists lose their fight against established facts, again. In this case, the facts about “…molecular reprogramming of the fetal germline…” and autism will continue to prevail.
Elsewhere, the trangenerational epigenetic inheritance (TGEI) of virus-driven pathology has been linked from two different herpes viruses to Alzheimer’s disease.
RNA sequencing from several brain regions linked detailed facts about quantized energy as information to differences in the genes that are expressed in donors with and without the disease.
See: RNA-Guided Human Genome Engineering
5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).
Watch the Trump administration force the NIH to drain the academic swamp, which includes those who applied for the patent on naturally occurring RNA interference with the claim that natural selection for quantized energy-dependent codon optimality was non-obvious.
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.