Light and life at base pair resolution (3)

See: The 5th Max Planck Epigenetics Meeting

LSM2-8 and XRN-2 selectively silence H3K27me3-marked genes in C. elegans by RNA decay

See also:

Polycomb proteins and 3D genome folding in gene regulation and cancer

Is preventing the virus-driven degradation of messenger RNA the link from food energy to ecological adaptations in P. pacificus via sympatric speciation? If so, the hecatombic evolution of all pathology might be prevented by food energy-dependent polycombic adaptations.

See: From Fertilization to Adult Sexual Behavior (1996)

Yet another kind of epigenetic imprinting occurs in species as diverse as yeast, Drosophila, mice, and humans and is based upon small DNA-binding proteins called “chromo domain” proteins, e.g., polycomb. These proteins affect chromatin structure, often in telomeric regions, and thereby affect transcription and silencing of various genes (Saunders, Chue, Goebl, Craig, Clark, Powers, Eissenberg, Elgin, Rothfield, and Earnshaw, 1993; Singh, Miller, Pearce, Kothary, Burton, Paro, James, and Gaunt, 1991; Trofatter, Long, Murrell, Stotler, Gusella, and Buckler, 1995). Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans (Adler and Hajduk, 1994; de Bono, Zarkower, and Hodgkin, 1995; Ge, Zuo, and Manley, 1991; Green, 1991; Parkhurst and Meneely, 1994; Wilkins, 1995; Wolfner, 1988). That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from alternative splicings of otherwise identical genes.

If our claims about epigenetic imprinting are true, the creation of sunlight prevents the virus-driven degradation of messenger RNA in C. elegans, which links mutations to P. pacificus via sympatric speciation in the context of the epigenetic effects of food and pheromones on energy-dependent reproduction.

See also: Unsealing of Christ’s Reputed Tomb Turns Up New Revelations

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Author: James Kohl

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