
…hydrophobic interactions may have catalytic roles also in other biological contexts, such as in polymerases.
Reported as: DNA is held together by hydrophobic forces 9/23/19
Researchers at Chalmers University of Technology, Sweden, disprove the prevailing theory of how DNA binds itself.
The prevailing theory was ridiculous. It included no global biogeochemical constraints on the virus-driven degradation of messenger RNA, which all serious scientists linked from mutations to all pathology.
See for comparison: From hydrogen atom transfer in DNA base pairs to ecosystems 7/31/16
For ridicule of all pseudoscientists who have failed to link the light-activated energy-dependent assembly of the microRNA-RNA-peptide nanocomplex, also known as the polycomb repressive complex, to hydrophobicity and the functional structure of supercoiled DNA, see this from 12/10/14:
For more information on how supercoiled DNA is linked from protection of the virus-driven degradation of messenger RNA to healthy longevity, see:
MicroRNA Networks Modulate Oxidative Stress in Cancer 9/11/19
…miRNAs are involved in ROS production or ROS-mediated function.
Investigating the interactions between ROS and miRNAs
…is expected to aid in the development of effective treatment/prevention strategies for cancer [and all virus-driven pathology.]
See also:
MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing 8/30/19
These results outline a new process for microRNAs in regulating alternative splicing and modulating stress resistance.
The results link light-activated microRNA biogenesis to viral latency across kingdoms via the physiology of reproduction and fixation of RNA-mediated amino acid substitutions in organized genomes via the modulation of energy-depenedent alternative splicing.
See also: MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing 8/30/19
I reiterate:
These results [DO NOT] outline a new process for microRNAs in regulating alternative splicing and modulating stress resistance.
See: From Fertilization to Adult Sexual Behavior (1996)
“Small intranuclear proteins” [light-activated endogenous substrates] generate “alternative splicing techniques of pre-mRNA” [aka microRNAs] “and, by this mechanism, contribute to sexual differentiation in at least two species…”
No new mechanisms of energy-dependent biophysically constrained RNA-mediated cell type differentiation have been discovered since 1964.
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
See also: