Lewis Thomas (revisited): 90K (1)

I should think we might fairly gauge the future of biological science, centuries ahead by estimating the time it will take to reach a complete comprehensive understanding of odor. It may not seem a profound enough problem to dominate all the life sciences, but it contains, piece by piece, all the mysteries” (p. 732). — Lewis Thomas as cited in The Scent of Eros: Mysteries of Odor in Human Sexuality (1995/2002)

All aspects of how the energy-dependent creation of the sense of smell in bacteria must be linked to our visual perception of energy and mass across the time-space continuum were detailed in Olfaction Warps Visual Time Perception (2017)

The senior author, Wen Zhou, Institute of Psychology, CAS was equally inspired by the works of Lewis Thomas, who in 1980 also asked:

WHAT are we going to do if it turns out that we have pheromones? What on earth would we be doing with such things? With the richness of speech, and all our new devices for communication, why would we want to release odors into the air to convey information about anything? We can send notes, telephone, whisper cryptic invitations, announce the giving of parties, even bounce words off the moon and make them carom around the planets. Why a gas, or droplets of moisture made to be deposited on fenceposts?

Her professor, Denise Chen (a former student of Martha McClintock) introduced me to Wen Zhou during an olfactory conference sometime around the turn of the century. Denise added that the book I co-authored inspired her to study the sense of smell. Studies across three generations have made the claims about God’s Creation irrefutable, and none can be placed by any intelligent researcher back into the context of neo-Darwinian theory or Big Bang cosmology.

There are no competing theories about endogenous RNAs. Light-activated microRNA biogenesis is the obvious link from endogenous substrates (the microRNAs) to biophysically constrained viral latency across kingdoms.

Genome-wide analysis of long noncoding RNAs, microRNAs, and mRNAs forming a competing endogenous RNA network in repeated implantation failure 8/19/19

…competing endogenous RNA (ceRNA) theory.

They claim that the nutrient-dependent pheromone-controlled “…regulatory mechanism of the lncRNA–miRNA–mRNA network in repeated implantation failure (RIF) is unclear.”

The would be true only if biophysically constrained RNA-mediated cell type differentiation in species from microbes to humans had not been detailed in our section on molecular epigenetics From Fertilization to Adult Sexual Behavior  (1996)

Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans (Adler and Hajduk, 1994; de Bono, Zarkower, and Hodgkin, 1995; Ge, Zuo, and Manley, 1991; Green, 1991; Parkhurst and Meneely, 1994; Wilkins, 1995; Wolfner, 1988). That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from alternative splicings of otherwise identical genes.

The problem with telling the truth arose because sex researchers did not like our claim about sexual orientation in yeasts.

Parenthetically it is interesting to note even the yeast Saccharomyces cerevisiae has a gene-based equivalent of sexual orientation (i.e., a-factor and alpha-factor physiologies). These differences arise from different epigenetic modifications of an otherwise identical MAT locus (Runge and Zakian, 1996; Wu and Haber, 1995).

Some of them still explain sexual differentiation in the context of “magic traits.”

See: Genetic dissection of assortative mating behavior 2/17/19

Ecologically relevant mating cues (sometimes known as “magic traits” [2,6]) are now predicted to be widespread in nature [6,7], and the last few years have seen considerable progress in our understanding of their genetic basis.

For relevant mating cues to have a genetic basis, genes would need to automagically create themselves. Only then could the genetic basis for ecologically relevant magic traits be linked to the magic of neo-Darwinian theory without consideration for the light-activated assembly of the microRNA-RNA-peptide nanocomplex that biophysically constrains the creation of energy-dependent supercoiled DNA. Supercoiled DNA protects all organized genomes from the virus-driven degradation of messenger RNA. That means the virus-driven theft of energy can be linked from what is known about the Creation of sunlight and water to protection from all virus-driven pathology.

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Author: James Kohl

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