Kohl and Francoeur at 25 (1)

The Scent of Eros: Mysteries of Odor in Human Sexuality (1995/2002)

Environmental heterogeneity and population differences in blue tits personality traits (2016)

The pace-of-life syndrome hypothesis predicts that habitat-specific selective pressures will favor the coevolution of personality, physiological, and life-history phenotypes.

Darwin’s “conditions of life” predicted that life-history phenotypes were energy-dependent and biophysically constrained by the physiology of reproduction.

See: Mitochondrial origins of fractional control in regulated cell death 3/21/19


These results suggest that environmental constraints can select subpopulations not only based on genetic composition, protein abundances, but also based on CCV in organelle abundances.

Energy-dependent environmental constraints on cell-to-cell variability (CCV) have been linked from the measurement of fluorescence to the effective treatment and/or prevention of cancer. That claims was reported as:

The ability of different peptides to inhibit autophosphorylation of EGFR is presented by the decrease of the fluorescent signal (Y axis).

For comparison, the Mitochondrial origins of fractional control was reported as: Mount Sinai and IBM researchers uncover key to greater efficacy in cancer treatment 3/21/19

Cells die when met with bacteria, malnourishment, or viruses. But also, to promote normal function, our bodies eliminate billions of cells each day–a process known as “programmed cell death” or apoptosis. Mitochondria, often referred to as the powerhouse of the cell because of their ability to produce cellular energy….

My comment:

Malnourishment causes the proliferation of viruses that links the virus-driven degradation of messenger RNA from mutations to all diseases.

The creation of anti-entropic virucidal light typically prevents the transgenerational epigenetic inheritance of disease via the food energy-dependent pheromone-controlled physiology of reproduction in species from microbes to humans.

All serious scientists understand that in the context of McEwen et al., 1964: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

Ages 10+ can learn the facts about naturally occurring energy-dependent RNA interference via game play of Subatomic: An Atom-Building Board Game and Cytosis: A Cell Biology Board Game

McEwen et al., (1964) wrote:

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

The proliferation of viruses clearly links the degradation of messenger RNA from the loss of ATP needed for cell type differentiation to constraint breaking mutations and all diseases.

The history of constraint-breaking mutations links the Virus-mediated archaeal hecatomb in the deep seafloor to mutation-driven diseases in the context of the Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.

This was placed into the context of Past 5,000 years prolific for changes to human genome

The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.

See for comparison: Eukaryotic plankton diversity in the sunlit ocean

Diversity emerged at all taxonomic levels, both within the groups comprising the ~11,200 cataloged morphospecies of eukaryotic plankton and among twice as many other deep-branching lineages of unappreciated importance in plankton ecology studies. Most eukaryotic plankton biodiversity belonged to heterotrophic protistan groups, particularly those known to be parasites or symbiotic hosts.

Reports that diversity ’emerged’ in the context of competition between parasites and symbiotic hosts makes it perfectly clear that survival of hosts is energy-dependent and biophysically constrained by the physiology of pheromone-controlled reproduction in species from microbes to humans.

But see: The Human Helix

The Cell Editorial Team pretends to know nothing about achiral glycine, the so-called “alpha helix breaker” as they link the magic of evolution to the energy-dependent creation of “The Human Helix” with no biophysical constraints whatsoever.



Author: James Kohl

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