The pace-of-life syndrome hypothesis predicts that habitat-specific selective pressures will favor the coevolution of personality, physiological, and life-history phenotypes.
Darwin’s “conditions of life” predicted that life-history phenotypes were energy-dependent and biophysically constrained by the physiology of reproduction.
These results suggest that environmental constraints can select subpopulations not only based on genetic composition, protein abundances, but also based on CCV in organelle abundances.
Energy-dependent environmental constraints on cell-to-cell variability (CCV) have been linked from the measurement of fluorescence to the effective treatment and/or prevention of cancer. That claims was reported as:
For comparison, the Mitochondrial origins of fractional control was reported as: Mount Sinai and IBM researchers uncover key to greater efficacy in cancer treatment 3/21/19
Cells die when met with bacteria, malnourishment, or viruses. But also, to promote normal function, our bodies eliminate billions of cells each day–a process known as “programmed cell death” or apoptosis. Mitochondria, often referred to as the powerhouse of the cell because of their ability to produce cellular energy….
The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.
See for comparison: Eukaryotic plankton diversity in the sunlit ocean
Diversity emerged at all taxonomic levels, both within the groups comprising the ~11,200 cataloged morphospecies of eukaryotic plankton and among twice as many other deep-branching lineages of unappreciated importance in plankton ecology studies. Most eukaryotic plankton biodiversity belonged to heterotrophic protistan groups, particularly those known to be parasites or symbiotic hosts.
Reports that diversity ’emerged’ in the context of competition between parasites and symbiotic hosts makes it perfectly clear that survival of hosts is energy-dependent and biophysically constrained by the physiology of pheromone-controlled reproduction in species from microbes to humans.
But see: The Human Helix
The Cell Editorial Team pretends to know nothing about achiral glycine, the so-called “alpha helix breaker” as they link the magic of evolution to the energy-dependent creation of “The Human Helix” with no biophysical constraints whatsoever.