FDA’s ignorance: From roots to shoots (1)

See: CDC’s ignorance: From roots to shoots (1)

Facts about food safety linked vitamin C and vitamin D3 to fixation of amino acid substitutions and protection from coronavirus pathology (and other virus-driven pathologies) in my invited review of nutritional epigenetics: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems 4/11/14

The invited review linked what organisms eat from the physiology of reproduction to biophysically constrained viral latency across kingdoms. That may be why it was returned without review in 2014.

It refuted the pseudoscientific nonsense about mutation-driven evolution. Many people prefer pseudoscientific nonsense to facts about biophysically constrained viral latency.

A second invite led to publication on 4/18/18 as Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems.

The four year delay in dissemination of accurate information about how to prevent the virus-driven degradation of messenger RNA that links mutations to all pathology across kingdoms was manifested in this report:

‘Everything depends on where you got virus’: US & Russian top specialists explain odds of catching Covid-19 & surviving 3/8/20

 “We are aware of at least 40 coronaviruses”

Intelligent serious scientists know how to prevent ecological adaptations in the 40 coronaviruses and in other viruses. The adaptations in viruses arise due to normal ecological variation via nutrient stress and/or social stress, and also due to the vaccine-induced reassembly of viruses and viral fragments.

See: Viruses Can Scatter Their Genes Among Cells and Reassemble 5/21/19

Adaptations in viruses are prevented when organisms consistently have enough food to ensure successful pheromone-controlled reproduction and sympatric speciation. Ecological variation and vaccine-induced changes are less likely to lead to adaptations in viruses, and more likely to lead to adaptations in all species via sympatric speciation.

Unfortunately, everything known to all serious scientists about biophysically constrained viral latency and sympatric speciation has been linked to evolution despite the claims in my refutation of neo-Darwinian pseudoscientific nonsense and Big Bang cosmology from: Nutrient-dependent/pheromone-controlled adaptive evolution: a model (6/14/13)

See for comparison: Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution 11/22/13

Koel et al. (p. 976) show that major antigenic change can be caused by single amino acid substitutions.

Serious scientists know that viruses do not evolve except in the context of hecatombic pathology.

See: Virus-mediated archaeal hecatomb in the deep seafloor (2016) for comparison to Eukaryotic plankton diversity in the sunlit ocean (2015)

Examples of adaptations to the viruses of different species from microbes to humans can now be compared via what happens when viruses ecologically adapt but not the species.

See:  “Everything depends on where you got the virus,” Favorov explains.

Epigenetically-effected gene polymorphisms determine who suffers and/or who dies from the strain of the virus. Gene polymorphisms also determine who adapts and lives via the transgenerational epigenetic effects of food energy-dependent pheromone-controlled constraints on viral replication.

For examples of transgenerational epigenetic inheritance that biophysically constrain viral latency in specific human populations, see:

See: Usefulness of COMT gene polymorphisms in North African populations 5/15/19

Food energy-dependent pheromone-controlled epigenetic effects on fixation of amino acid substitutions link genetic diversity in COMT gene polymorphisms to the history of human settlements, origins of ethnicity, healthy longevity, and/or all pathologies.

Viruses adapt via energy-dependent fixation of amino acid substitutions when host immunity is compromised by nutrient stress and/or social stress. People could be saved by vitamin C and vitamin D3 supplements that biophysically constrain EDAR V370A.

See also: Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk

The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to have occurred circa 20,000 y ago.

Nothing published by serious scientists supports claims about positive selection that occurred circa 20,000 y ago.

Those claims are based on theories touted by biologically uninformed theorists.

See for instance my review of The Rocks Were There, which was published by biologically uninformed science idiots on 2/27/20

Serious scientists start with God’s Creation of energy as information 3/1/20

Five years after “Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system” showed that the weekend resurrection of the bacterial flagellum in P. fluorescens could be observed, they use a definition of evolution and claim that “Evolution is definitely observable and (as we showed) testable.”

That’s true, but all attempts to put whatever else has been observed and tested back into the context of neo-Darwinian pseudoscientific nonsense across billions to millions of years have failed.

The triumph of common sense linked claims about God’s Creation of “Subatomic” particles from the creation of the “Periodic” table to biophysically constrained viral latency via “Cytosis” across all “Ecosystems” via Mendelian genetics and the game, “Genotype” for ages 14+.

Other readers need only start with Darwin’s “conditions of life” and link them from the food energy-dependent pheromone-controlled physiology of reproduction in bacteria to biophysically constrained coronavirus viral latency and/or to effective cancer treatment or prevention of cancer via microRNA-mediated changes in amino acids and supercoiled DNA.

For comparison, see their Appendix 3 “Amino Acid Codons”

Food energy-dependent codon optimality is controlled by the metabolism of food to species-specific pheromones, which prevent the mutations that most biologically uninformed theorists continue to link to claims about evolution over more than the past 5-10000 years.

These theorists seem to have learned nothing since the 1994 publication of “Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.)”

Indeed, if Downard and Jackson have learned anything about the conserved food energy-dependent regulation of genetic processes, they do not take what has been learned outside the context of ridiculous theories. Instead, they expound upon the theories, which is how theorists prevent scientific progress.

See also: Probing Ovulatory-Cycle Shifts in Women’s Preferences for Men’s Behaviors 3/4/20 reported on 3/9/20 as: Study: Women’s hormonal cycles do not affect preferences for men’s behavior

If true, women are exceptions to all the facts about biologically based cause and effect that we published in our 1996 review: From Fertilization to Adult Sexual Behavior

If the claims from my life history of publications and presentations are true, the claims from biologically uninformed science idiots (e.g., the psychologists probing ovulatory cycle shifts) may lead to the virus-driven suffering and premature death of everyone you ever loved.

See for comparison: [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)]

…results obtained during last 10-15 years are discussed. The adaptive role of cytogenetic and other observed pheromonal effects is considered. The possible existence of interorganism systems of genetic regulation is discussed, the search for and study of which may help in more complete understanding of the regularities of functioning of genetic material.

See also: Plasma testosterone level and sexual behavior of couples (1978)

The significance of the nutrient-dependent pheromone-controlled periodic fluctuation in the male’s testosterone was linked from entrainment to the wife’s menstrual cycle via research on dominant male rhesus monkeys. That research suggested that pheromonal communication exists between the two partners in which “…the female informs the male that she has ovulated and he responds, like the dominant rhesus monkey, with an increase in his testosterone level facilitating his entire sexual response cycle.”

The research that was reported before 15 years before publication of [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)] (1994) suggested that a molecular mechanism existed to reenforce the pair bonding of couples and also to reenforce their reproductive capacity.

That claim exemplifies the young earth creationist perspective, which is shared among people of all Abrahamic faiths. God’s Creation of sunlight and water have since been linked from oxidative phosphorylation to all oxygen-dependent viral latency and all biophysically constrained cell type differentiation via the pheromone-controlled physiology of reproduction in bacteria.

Indeed, 25 years after our publication of “The Scent of Eros: Mysteries of Odor in Human Sexuality“serious scientists have again asserted the fact that:

“…naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology.”

The coherent organized biology is also exemplified by the fact that Olfaction Warps Visual Time Perception 3/17/17

See also: Difference in mass resulting from the change of a single amino acid

The mass of normal alpha chain is 15126.3 Da and that of the normal beta chain 15867.5, the changes induced by single point mutations are given above (only those allowed by the genetic code are given). As an example the change from Asp to His will increase the normal mass by 22 units and the reverse change will decrease the mass by the same amount.

God’s Creation of the sense of smell in bacteria was linked to our visual perception of energy and mass across the space-time continuum via our sense of smell and the physiology of our pheromone-controlled reproduction. The warped perspectives of pseudoscientists, especially the neo-Darwinian theorists and atheists can be viewed in the context of these facts. Feedback loops link odor and pheromone signaling with reproduction (2005)

The failure of the CDC and the FDA to link God’s Creation of sunlight and water from oxidative phosphorylation to biophysically constrained viral latency and all biodiversity on Earth is an epic failure that can be linked to the failure of the NIH to promote nutrient-dependent pheromone-controlled healthy longevity via everything that links roots to shoots in Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)

The synthesis of RNA in isolated thymus nuclei is ATP dependent.



Author: James Kohl

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