Energy-dependent thymic involution vs evolution (2)

By: James V. Kohl | Published on: December 12, 2018

Summary: The “initiator” RNA links the virus-driven degradation of messenger RNA from constraint-breaking mutations to all pathology via what is known about biophysically constrained viral latency in the context of the microRNAome. That is what scientific creationists have placed into the context of energy-dependent thymic involution vs evolution.
MicroRNA-mediated therapy prevents thymic involution. Energy-dependent light-activated microRNA biogenesis will soon be linked from the ability of light to override carbon as a major regulator of ASN1 and GLN2 in etiolated seedlings to healthy longevity at every level of biological organization…
Identification of potential microRNAs associated with Herpesvirus family based on bioinformatic analysis

MicroRNAs (miRNAs) are known key regulators of gene expression on posttranscriptional level in many organisms encoded in mammals, plants and, only recently recognized, also several viral families.

The difference between a pre-miRNA and a pre-mRNA has become more important in the context of light-activated microRNA biogenesis because cell type differentiation is energy-dependent and light overrides carbon as a major regulator of energy-dependent cell type differentiation in etiolated seedlings. Also, there is no such thing as a response QTL outside the context of energy-dependent cell type differentiation. That is why theorists won’t admit they use the term QTL to avoid the link from the energy-dependent creation of microRNAs to species-specific changes in plants and animals across kingdoms.
Using a Classifier Fusion Strategy to Identify Anti-angiogenic Peptides

Accurate identification of anti-angiogenic peptides may provide significant clues to understand the essential angiogenic homeostasis within tissues…

An isoform and a peptide are the same. QTLs and microRNAs are the same. QTLs are microRNAs and isoforms are peptides that link amino acid substitutions to cell type differentiation.
The name game is escalating rapidly. Researchers from Iran reported: Competing endogenous RNA (ceRNA) cross talk and language in ceRNA regulatory networks: A new look at hallmarks of breast cancer

…we propose for the first time the “ceRnome” as a new term in the present article for RNA research.

No one needs another term and no one needs competing endogenous RNA to be linked to ceRNA regulatory networks in the context of the ceRome.  This link from light-activated microRNA biogenesis to cell type differentiation via the microRNAome was reported in 2003: Light- and Carbon-Signaling Pathways. Modeling Circuits of Interactions with my emphasis.

Boolean logic was used to model the effect of these carbon/light interactions on three target genes involved in nitrogen assimilation…. light was able to override carbon as a major regulator of ASN1 and GLN2 in etiolated seedlings.

Researchers in Iran have also reported on microRNAs in cancer stem cells: Biology, pathways, and therapeutic opportunities

…endogenous, small noncoding RNA molecules control gene expression at the posttranscriptional level.

…Our current knowledge of miRNA functions in CSCs may now be used for cancer diagnostic and prognostic purposes. In addition, when combined with recent technical advances in the in vivo delivery of miRNAs, we are now in an excellent position to develop strategies that harness miRNA interference

See also (from Iran): MiRNAs: Biology, Biogenesis, their Web-based Tools, and Databases

INTRODUCTION: MicroRNAs (miRNAs), which are evolutionarily conserved, and endogenous non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The biogenesis of miRNAs occurs in the nucleus. Then, in the cytoplasm, they are assembled along with some proteins in a ribonucleoprotein complex called RISC. miRNA component of the RISC complex binds to the complementary sequence of mRNA target depending on the degree of complementarity, and leads to mRNA degradation and/or inhibition of protein synthesis. miRNAs have been found in eukaryotes and some viruses play a role in development, metabolism, cell proliferation, growth, differentiation, and death.

…We have categorized them into different classes including databases for viral miRNAs, and plant miRNAs, miRNAs in human beings, mice and other vertebrates, miRNAs related to human diseases, and target prediction, and miRNA expression.

Why are some researchers from Iran reporting on microRNA biogenesis as other researchers from Iran report on competing endogenous RNA. And why are others from Iran reporting on harnessing microRNA interference?
Even if they are not deliberately attempting to obfuscate what is known to scientific creationists in the Republic of Korea about the creation of sunlight and microRNA-mediated cause and effect, Iranian researchers are doing it.
Is this why? RNA-mediated gene fusion in mammalian cells

…we identified an endogenous RNA AZI1 that functions as the “initiator” RNA to induce TMPRSS2–ERG fusion. RNA-driven gene fusion demonstrated in this report provides important insight in early disease mechanisms, and could have fundamental implications in the biology of mammalian genome stability, as well as gene-editing technology via mechanisms native to mammalian cells.

The “initiator” RNA links the virus-driven degradation of messenger RNA from constraint-breaking mutations to all pathology via what is known about biophysically constrained viral latency in the context of the microRNAome. Simply put, that is what scientific creationists have placed into the context of energy-dependent thymic involution vs evolution. If microRNA-mediated therapy can prevent thymic involution, energy-dependent microRNA biogenesis will soon be linked to healthy longevity at every level of biological organization mentioned in Biblical Genesis.
This poses a threat to evolutionists because as the Islamic creationist, Yahya, Harun [Adnan Oktar] wrote: Evolutionists Cannot Account for the Origin of the Sense of Smell

Adnan Oktar

In 2010, Oktar was selected as one of the top fifty of The 500 Most Influential Muslims in the World by the Royal Islamic Strategic Studies Centre of Jordan for his dissemination of creationism in an Islamic context, and other extensively distributed publications on Islamic topics.[35]

July 2018 arrest and criminal charges

On 11 July 2018, the financial crimes section of the Turkish police detained Oktar and over 160 of his associates on charges including forming a criminal enterprise, financial fraud and sexual abuse.[36]

As others wait to see what happens next, they should keep in mind that the problem still seems to be that Evolutionists Cannot Account for the Origin of the Sense of Smell as noted in The Miracles of Smell and Taste.


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