Guest Editor Rebecca L. Skalsky
Guest Editor Dr. Eva Gottwein
Non-coding RNAs (ncRNAs) are key regulators in anti-viral responses and play diverse roles in various aspects of infection, including virus replication, persistence, and pathogenesis. In addition to host ncRNAs that are influenced and/or utilized during infection, both DNA and RNA viruses produce regulatory ncRNAs. These molecules can act to modulate gene expression, such as microRNAs encoded by several DNA viruses, or control RNA stability or epigenetic processes, such as some viral long ncRNAs. Ongoing questions include how viral ncRNAs contribute to immune evasion, whether ncRNAs act as virulence factors, how viruses hijack host ncRNAs, and how both viral and host ncRNAs coordinate to benefit virus replication.
This Special Issue will group together works on the latest advances in non-coding RNA studies related to virus infections in humans and animal model systems.
I placed the latest advances in non-coding RNA studies related to virus infections in humans and animal model systems into the context of a presentation during the 2017 virtual conference on Precision Medicine.
See: Energy as information and constrained endogenous RNA interference and this blog post from 5/8/18: Energy as information and constrained endogenous RNA interference
See for comparison: Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene (2011) by Rebecca L. Skalsky and Bryan R. Cullen
See also: Analysis of Viral and Cellular MicroRNAs in EBV-Infected Cells (2017) by Rebecca L. Skalsky
See also: Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma (2018) by senior author Eva Gottwein
Although it is tempting to submit a manuscript to guest editors who appear to know how to link light-activated microRNA biogenesis to healthy longevity via biophysical constraints on viral latency, I am not likely to submit anything else for publication. I don’t know who is likely to claim that the information I have already published in peer-reviewed journals during the past 22 years is new information when they use it in their publications.
But, all serious scientists know how academics with no new ideas must steal from those who have continued to pursue experimental evidence of top-down causation and link it from the creation of quantized energy to biophysically constrained viral latency and the prevention of all pathology.
Here’s what happens. See: Kalevi Kull: Censorship & Royal Society Evo Event
Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull