Chemogenetic kinetics (7): DHA vs consensus (2)

Molecular Dynamics Study of the Hybridization between RNA and Modified Oligonucleotides 9/25/19

…demonstrated that MD [Molecular Dynamics] simulations with [light-activated] polarizable force fields are useful for the understanding and design of modified nucleic acids.

My summary: The light-activated assembly of the microRNA-RNA-peptide nanocomplex links carbon fixation from the Creation of differences in base pairs to biophysically constrained viral latency and healthy longevity via the pheromone-controlled physiology of reproduction in species from microbes to humans.

For support of my summary, see: Single-Molecule Topochemical Analyses for Large-Scale Multiplexing Tasks 9/25/19

By mechanical unfolding of the hairpin, individual internal loops are sequentially interro-gated for the binding of each miRNA. Using this so-called topochemical spatiotemporal analysis, we were able to achieve sub-picomolar detection limits of miRNAs. We anticipate this new single-molecule topochemical analysis can massively analyze single-molecule targets.

For information on how scientific progress has led to detecting virus-driven changes in single-base mismatches linked to errors in protein folding see:

Synergy of peptide-nucleic-acid and spherical nucleic acid enabled quantitative and specific detection of tumor exosomal microRNA 9/25/19

The synergy between PNA and SNA makes SEEmiR sensor achieving a broad dynamic range (from 100 aM to 1 nM) with a detection limit… capable of distinguishing a single-base mismatch.

Now, ask yourself why everyone does not already know that  The Darwinian ‘Struggle for Existence’ is Really About Balance 8/29/19

The virus-driven degradation of messenger RNA is the threat to that balance, but pseudoscientists refuse to acknowledge the threat. Instead, some of them claim that global warming is the threat.

See: Projected declines in global DHA availability for human consumption as a result of global warming 9/12/19

Solutions are needed to slow the rate of DHA loss in order to protect this valuable, patchily distributed, resource for future human generations and ecosystems.

Where do biologically uninformed science idiots, who don’t know how DHA is Created, think that DHA losses go? Projections from mathematical models are worthless compared to what is known to serious scientists about food energy-dependent links from angstroms to ecosystems.

See: The role of docosahexaenoic and the marine food web as determinants of evolution and hominid brain development: the challenge for human sustainability 1/21/12

See: The tipping point (revisited): 88K (1) 6/17/19

Light-activated microRNA biogenesis links the energy-dependent creation of docosahexanoic acid from the assembly of the microRNA-RNA-peptide nanocomplex to biophysically constrained viral latency, which links physics, chemistry, and molecular epigenetics to all biodiversity via food energy-dependent social networks of interaction.

See: A key metabolic gene for recurrent freshwater colonization and radiation in fishes (5/31/19)

…DHA allows for quantum transfer and communication of π-electrons…

…deficiency in docosahexaenoic acid (DHA), an essential ω-3 fatty acid, can constrain freshwater colonization by marine fishes.

The creation of subatomic particles (energy as information) links epigenetic effects of dietary DHA on consciousness from microRNAs in milk exosomes to sex differences in autism and all differences in all cell types of all mammals.

See: Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns (7/28/18)

See also: Anesthesia Points to Deeper Level ‘Quantum Channels’ as Origins of Consciousness (3/23/15)

… the US-Canadian team… had previously shown anesthetic binding in ‘quantum channels’, non-polar arrays of amino acid pi resonance clouds, winding through microtubules.

Proponents of vaccines that contain viruses or viral fragments must now ignore the past 7 years of scientific progress since I published: Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors 3/15/12

I wrote:

…ignoring the likely effects of docosahexaenoic acid in the maternal and postnatal diet on LH and on neuronal development…

I cited the most appropriated research at that time. Sex differences in the relationship of dietary fatty acids to cognitive measures in American children (2011)

And then what happened?

See: 9/16/19
This is awesome and so important to understand 9/16/19
New #viruses with possible connections to human disease are still being discovered on a fairly regular basis. The tools used to identify such viruses are also growing in sophistication…exciting times! https://twitter.com/derya_/status/

My responses:

The virus-driven degradation of messenger RNA has been linked to all pathology via Eukaryotic plankton diversity in the sunlit ocean (2015) and  Virus-mediated archaeal hecatomb in the deep seafloor (2016).

Games for ages 10+ can teach your children more than what people like @microbeminded2 have learned.
Subatomic
Periodic
Cytosis
Virus Expansion

Genotype

However, there may not be enough time left for you to save your children or to save humanity, since biologically uninformed theorists failed to note the importance of docosahexanoic acid to biophysically constrained viral latency in all living genera.

Author: James Kohl

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