Category: RNA-mediated gene silencing
The tipping point (revisited): 101K (1)
The tipping point (revisited): 100K (1) 3/30/20 4/22/20 update: Items: 1 to 20 of 101001 More than 101,000 indexed publications that mention “microRNA” link virus-driven…
The tipping point (revisited): 98K (5)
I blog-posted The tipping point (revisited): 98K (4) 10 days ago. During my vacation, 440 more publications were added to ~98,000 publications that link light-activated…
The tipping point (revisited): 98K (4)
Word-games and claims about beneficial mutations obfuscate the fact that light-activated carbon fixation is the link to microRNA-mediated viral latency and biophysically constrained ecological adaptations….
The tipping point (revisited): 96K (3)
Nutrient-dependent pheromone-controlled biophysically constrained viral latency prevents pathology in species from microbes to mammals via microRNA biogenesis. Watch as the latest results from my daily…
How to Profit from Suffering and Death (3)
Cellular survival over genomic perfection 11/15/19 Comprehensive DNA quality control pathways are therefore considered crucial to preserving genomic health. Femtosecond blast of UV light were…
MicroRNA-mediated, since 1964 (2)
A late Miocene hominid partial pelvis from Hungary 9/17/19 …this fossil lacks the long lower ilium that characterizes chimpanzees, gorillas and orangutans, associated with their…
Trans-kingdom RNA interactions (1)
The Creation of RNA is energy/ATP-dependent and microRNA-mediated. Alternative splicings of RNA link biophysically constrained viral latency from the Creation of sunlight to healthy longevity…
Weaponized health communication (5)
Weaponized health communication (4) Isn’t it time you stopped calling amino acid substitutions “mutations?” In 1992, I presented Luteinizing Hormone (LH): The link between sex…
MicroRNA-mediated enhancer-promoter chemistry
Summary: The claim that loop extrusion and homotypic attraction are two antagonistic fundamental forces that are linked to what enhancer-promoter contacts and chromatin domains physically…
MicroRNA-controlled quantitative trait loci (QTLs)
See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model (6/14/13) A good model predicts. In my refutation of the neo-Darwinian pseudoscientific nonsense touted in Mutation-Driven Evolution (6/14/13), I…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.