Category: RNA-mediated epigenetic regulation of gene expression
The tipping point (revisited): 88K (3)
The Woman Who Revealed the Missing Link Between Viruses and Cancer 6/17/19 In 1911, virologist Peyton Rous discovered the Rous sarcoma virus, which he concluded…
QTLs: Your introduction to VirusGate (2)
John Brunstein toys with the twisted facts about epigenetically effected top-down causation and represents the creation of genes and phenotypes in the context of: Quantitative…
Combating ignorance to fight disease (2)
Frequent birth of de novo genes in the compact yeast genome M. Mar Alba wrote: we are only starting to realize how common this is,…
10,000 reasons to believe in biophysical constraints (revisited)
On January 29, 2019 to January 30, 2019, my Tweets made more than 10,000 impressions (total 12,200). I followed-up on the claim about A cure…
From microRNA.pro to quantumsouls.pro (2)
Caffeine-inducible gene switches controlling experimental diabetes Capitalizing on routine cultural habits, therapies based on such systems should seamlessly integrate into people’s lifestyle, and therefore could…
Hide and seek with science facts (4)
Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining They invented a new term to obfuscate facts about food energy-dependent RNA-mediated DNA repair….
10,000 reasons to believe in biophysical constraints (3)
See: The Darwin Code by Greg Bear Charles Darwin was wise enough not to pin down what he could not see or know, and so,…
The tipping point (revisited): 78,000 publications (2)
Summary: The conserved molecular mechanisms of circadian rhythms and estrogen receptor polymorphisms are linked to all energy-dependent polymorphisms via the creation of sunlight, which is…
The tipping point (revisited): 78,000 publications (3)
Structural basis of the nucleosome transition during RNA polymerase II passage Kujirai T, Ehara H, Fujino Y, Shirouzu M, Sekine S, Kurumizaka H Science (2018)…
The ‘confusant’ hypothesis
Summary: Confused researchers at Rockefeller should meet with Bruce McEwen to learn why he said my 1992 model of biophysically constrained cell type differentiation could…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.