Category: RNA-directed DNA methylation
Multigenerational epigenetic inheritance (4)
One year ago, Kevin J. Mitchell published Innate How the Wiring of Our Brains Shapes Who We Are My review: Ignoring light-activated microRNA biogenesis 10/16/18…
Patented Creation vs Evolution of Disease (7)
Insights into the ecological roles and evolution of methyl-coenzyme M reductase-containing hot spring Archaea 10/8/19 To unwind the evolutionary history of mcr-containing microorganisms, we used…
Trans-kingdom RNA interactions (1)
The Creation of RNA is energy/ATP-dependent and microRNA-mediated. Alternative splicings of RNA link biophysically constrained viral latency from the Creation of sunlight to healthy longevity…
Nutrient-dependent Pheromone-controlled cures (4)
Who believes I am losing followers and engagements on Twitter @microRNApro after 3 SNPs were linked from the stability of organized human genomes to homosexual…
Nutrient-dependent Pheromone-controlled cures (3)
Most intelligent people know there will always be psychopathology. Deadly weapons, such as guns, and training are better protection and they are less expensive than…
Sunlight, hydrophobicity and biodiversity (1)
A five-coordinate Mn(iv) intermediate in biological water oxidation: spectroscopic signature and a pivot mechanism for water binding 11/17/15 …a multi-step process that involves the redox-active…
Weaponized health communication (5)
Weaponized health communication (4) Isn’t it time you stopped calling amino acid substitutions “mutations?” In 1992, I presented Luteinizing Hormone (LH): The link between sex…
MicroRNA-mediated enhancer-promoter chemistry
Summary: The claim that loop extrusion and homotypic attraction are two antagonistic fundamental forces that are linked to what enhancer-promoter contacts and chromatin domains physically…
QTLs: Your introduction to VirusGate (2)
John Brunstein toys with the twisted facts about epigenetically effected top-down causation and represents the creation of genes and phenotypes in the context of: Quantitative…
Systems biology vs pseudoscientific nonsense
A de novo transcriptome assembler was substituted for the light-activated assembly of the microRNA-RNA-peptide nanocomplex. See: Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.