Posted in MicroRNA biogenesis Model Organisms Pheromones Physics RNA interference

MicroRNA biogenesis vs Big Bang abiogenesis

Could the Big Bang be Wrong? …he came up with a complicated oscillating-universe model… The energy-dependent oscillations link light-activated carbon fixation from microRNA biogenesis to…

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Posted in Adaptations Autophagy Diseases & Disorders Ecology Model Organisms Nutrigenomics Pheromones RNA interference What's in the News

Ecological Adaptations: From Angstroms to Ecosystems (2)

From the time I published my review of biophysically constrained nutritional epigenetics, which refuted the neo-Darwinian nonsense about mutation-driven evolution, 2834 more publications have mentioned…

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Posted in Adaptations Diseases & Disorders Ecology Human Brain Model Organisms Pheromones RNA interference

Kohl and Francoeur at 25 (8)

Epigenetic Regulations in Neuropsychiatric Disorders (4/4/19) This article is part of the Research Topic: Genetics and Epigenetics of Psychiatric Diseases For a historical perspective on…

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Posted in Adaptations Diseases & Disorders Ecology Model Organisms Pheromones RNA interference

Olfaction and microRNA signaling constrain longevity (4)

See: RNAi from Petunias to Worms (2006) Small RNAs can also be used to turn off large portions of the genome near centromeres via the…

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Posted in Adaptations Alternative Splicings Diseases & Disorders Ecology Human Pheromones Model Organisms Pheromones RNA editing

The tipping point (revisited): 85,000 publications (3)

Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) The synthesis of RNA in…

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Posted in Adaptations Cytosis Diseases & Disorders Ecology Light Energy Model Organisms Pheromones RNA editing

The tipping point (revisited): 85,000 publications

microRNA Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death (1/25/19) …various activators and modulators of NR4A2 have…

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Posted in Adaptations Autophagy Diseases & Disorders Ecology MicroRNA biogenesis microRNA editing Pheromones Variations

Epic failure of the FDA: Gottlieb resigns (2)

Epic failure of the FDA: Gottlieb resigns (1) We didn’t know it was possible for cells to survive crisis; we didn’t know autophagy is involved…

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Posted in Adaptations Diseases & Disorders Ecology MicroRNA biogenesis Model Organisms Pheromones

DS Wilson’s view of biophysically constrained life (3)

A Different Kind of Theory of Everything (2/19/19) 1) In 1964, during a lecture at Cornell University, the physicist Richard Feynman articulated a profound mystery…

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Posted in Adaptations Diseases & Disorders Ecology Light Energy Model Organisms Pheromones

Blood music orchestrates human life (3)

Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine LearningPotential Excessive Testing at Scale: Biomarkers, Genomics, and Machine LearningPotential Excessive Testing at Scale: Biomarkers, Genomics,…

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Posted in Adaptations Alternative Splicings base editing biophotonics Diseases & Disorders Ecology Pheromones RNA interference RNA–Mediated Epigenetic Heredity

Light-activated carbon fixation (2)

Raman‐activated cell sorting and metagenomic sequencing revealing carbon‐fixing bacteria in the ocean 5/4/18 …anaplerotic CO2 fixation in PR containing Dokdonia sp. MED134 provided up to…

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