Category: MicroRNA
The tipping point (revisited): 83,000 publications (1)
The tipping point (revisited): 82,000 publications (4) The tipping point (revisited): 82,000 publications (3) The tipping point (revisited): 82,000 publications (2) The tipping point (revisited):…
Do not call me Ishmael (3)
Summary: What kind of theory leaves out the energy-dependent changes that link the virus-driven degradation of messenger RNA to mutations and all pathology without linking…
Jan to Feb 1 2019 MicroRNA x 1352
Historical perspective (USA): The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression (12/2/14) In the following examples, only researchers from…
The tipping point (revisited): 82,000 publications (4)
MicroRNA Items: 1 to 20 of 81970 See for example: Oligonucleotide Therapeutics as a New Class of Drugs for Malignant Brain Tumors: Targeting mRNAs, Regulatory…
Light and life at base pair resolution (8)
When I encounter a relatively new term such as mitochondrial gene fragment that might be used instead of the term microRNA, I check the PubMed…
Sex-specific microRNA-mediated cancer treatment
Glioblastoma Pathway Signatures, Treatment Responses Differ Between Male, Female Patients …greater precision in the stratification of patients with GBM may be achieved through sex-specific molecular…
Happy Veteran’s Day 2018 (2)
Excerpt: “…in most cases, the RNA is an mRNA, carrying a protein coding sequence which is translated by the ribosomal machinery into a covalently attached…
Evolved suffering and death caused by statistical significance
Potential role of CSF cytokine profiles in discriminating infectious from non-infectious CNS disorders They used used a test for statistical significance in cytokine levels instead…
Theorists: The biggest threat to microRNA-mediated security
Summary: Kevin J. Mitchell is a biologically uninformed theorist. Food energy-dependent microRNA-mediated protein crowding in the cell types of human blood links the hemoglobin S…
Epigenetic effects on Eastern and Western societies
I linked natural selection for energy-dependent codon optimality from fixation of the EDAR V370A variant in mice to humans. See this Q and A with…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.