Category: microRNA editing
The tipping point (revisited): 98K (4)
Word-games and claims about beneficial mutations obfuscate the fact that light-activated carbon fixation is the link to microRNA-mediated viral latency and biophysically constrained ecological adaptations….
The tipping point (revisited): 98K (3)
Oded Rechavi bastardized the works of all serious scientists by representing energy-dependent biophysically constrained RNA interference (RNAi) as RNA inheritance, which he, and others like…
MicroRNA-mediated healthy longevity (1)
1/9/20 Selected additions from my PubMed search for: microRNA Too many additions link energy-dependent changes in microRNA biogenesis from the virus-driven degradation of messenger RNA…
The tipping point (revisited): 96K (3)
Nutrient-dependent pheromone-controlled biophysically constrained viral latency prevents pathology in species from microbes to mammals via microRNA biogenesis. Watch as the latest results from my daily…
A microRNA-mediated healthy New Year! Thank God (2)
MicroRNA-mediated suppression of P-glycoprotein by quantum dots in lung cancer cells 12/27/19 The interactions between adenosine triphosphate‐binding cassette (ABC) transporters and nano‐sized materials are attracting…
Light-activated PTEN-dependent viral latency (3)
Combination of KRAS gene silencing and PI3K inhibition for ovarian cancer treatment 12/16/19 …we propose using small interfering RNA (siRNA) therapeutics to directly target the…
microRNA-mediated sex differences (1)
For recent support of our claims from 23 years ago, see: Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier…
#SFN2019 to 2012: Hiding the facts (6)
Oxygen International “All normal cells have an absolute requirement for oxygen, but cancer cells can live without oxygen – a rule without exception. “Deprive a…
Chemogenetic kinetics (7): DHA vs consensus (4)
Mammalian Y RNAs are modified at discrete guanosine residues with N-glycans 9/30/19 …mammalian cells use RNA as a third scaffold for glycosylation in the secretory…
The tipping point (revisited): 91K (1)
See first: Trans-kingdom RNA interactions (1) See also: microRNA See: Items 1 to ~91000 Nanopolystyrene-induced microRNAs response in Caenorhabditis elegans after long-term and lose-dose exposure…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.