Category: MicroRNA biogenesis
Multigenerational epigenetic inheritance (4)
One year ago, Kevin J. Mitchell published Innate How the Wiring of Our Brains Shapes Who We Are My review: Ignoring light-activated microRNA biogenesis 10/16/18…
Patented Creation vs Evolution of Disease (5)
The 2019 Nobel Prize in Physics – Tuesday 8 October The 2019 Nobel Prize in Physiology or Medicine was awarded to researchers who linked God’s…
Patented Creation vs Evolution of Disease (2)
See: Patented Creation vs Evolution of Disease (1) 10/2/19 The light-activated assembly of the microRNA-RNA-peptide nanocomplex (aka the polycomb repressive complex) has been linked to…
The tipping point (revisited): 92K (1)
The BioLuminescent‐OptoGenetic in vivo response to coelenterazine is proportional, sensitive, and specific in neocortex 9/23/19 BioLuminescent (BL) light production can modulate neural activity and behavior…
Chemogenetic kinetics (2): Extinction
Biologically uninformed theorists failed to link light-activated energy-dependent “conditions of life” to biophysically constrained viral latency. That led them to ignore the consequences of virus-driven…
Trans-kingdom RNA interactions (3)
Intracellular innate immune surveillance devices in plants and animals 12/2/16 Excerpts: 1) In plants and animals, innate immunity involves both cell surface receptors (1) and…
Nutrient-dependent Pheromone-controlled cures (3)
Most intelligent people know there will always be psychopathology. Deadly weapons, such as guns, and training are better protection and they are less expensive than…
Nutrient-dependent Pheromone-controlled cures (2)
See: Nutrient-dependent Pheromone-controlled cures (1) My summary: They linked one base pair and one amino acid in a light-assembled microRNA-RNA-peptide nanocomplex to protection from nutrient…
Lewis Thomas (revisited): 90K (7)
Epigenetic effects on the light-activated microRNA-mediated creation of enzymes, hormones, and receptors et al., affect the behavior of all living genera. See: Pheromones and Nutritional…
Lewis Thomas (revisited): 90K (2)
For Alfred Russel Wallace, Natural Selection Opened the Door to Teleology 8/14/18 While natural selection was Darwin’s naturalistic drive train, Wallace found that natural selection…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.