Posted in Adaptations base editing biophotonics Diseases & Disorders Ecology Light Energy RNA interference RNA methylation RNA-directed DNA methylation

Systems biology vs pseudoscientific nonsense

A de novo transcriptome assembler was substituted for the light-activated assembly of the microRNA-RNA-peptide nanocomplex. See: Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance…

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Posted in Adaptations Cytosis Diseases & Disorders Ecology Human Pheromones Light Energy Model Organisms

Ecological Adaptations: From Angstroms to Ecosystems (1)

The pseudoscientific nonsense touted about Katie Bouman and her involvement in creating the imaginary image of the black hole led to suspension of her twitter…

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Posted in Adaptations biophotonics Diseases & Disorders Ecology Light Energy Physics RNA interference

Light and life-sucking black holes (2)

Ethan Siegel may be the first to have responded, without attribution, to my claims in Light and life-sucking black holes (1) See: Could All Our…

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Posted in Adaptations base editing biophotonics Cytosis Ecology Light Energy Physics Scientific Discoveries Subatomic

Life and light-sucking black holes (1)

From Fertilization to Adult Sexual Behavior (1996) We linked energy-dependent RNA-mediated cell type differentiation to all biodiversity via the physiology of reproduction in the molecular…

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Posted in Adaptations Alternative Splicings base editing Cytosis Diseases & Disorders Ecology Light Energy Subatomic

Olfaction and microRNA signaling constrain longevity (3)

Genetic compensation triggered by mutant mRNA degradation 4/3/19 Transcriptome analysis in alleles displaying mutant mRNA decay reveals the upregulation of a substantial proportion of the…

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Posted in Adaptations Autophagy Cytosis Diseases & Disorders Ecology Light Energy Physics RNA interference Subatomic

Olfaction and microRNA signaling constrain longevity (2)

Olfaction and microRNA signaling constrain longevity (1) 3/30/16 The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in…

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Posted in Adaptations Alternative Splicings Autophagy base editing Cytosis Diseases & Disorders Ecology Light Energy microRNA editing Physics RNA editing RNA interference

Kohl and Francoeur at 25 (6)

Excerpt: Natural selection for energy-dependent codon optimality links what animals like to eat to biophysically constrained viral latency vira the physiology of their pheromone-controlled reproduction…

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Posted in Adaptations Cytosis Diseases & Disorders Ecology Light Energy Model Organisms Pheromones RNA editing

The tipping point (revisited): 85,000 publications

microRNA Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death (1/25/19) …various activators and modulators of NR4A2 have…

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Posted in Adaptations biophotonics Diseases & Disorders Ecology Light Energy Model Organisms Subatomic

Kohl and Francoeur at 25 (3)

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection 3/29/19 Bacteriophages promote bacterial infection by directly triggering a maladaptive anti-viral immune response. In the…

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Posted in Adaptations biophotonics Cytosis Diseases & Disorders Ecology Light Energy Physics RNA interference Subatomic

Biophysical constraints on RNA synthesis (3)

Excerpt: This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on DNA base pairs in solution and RNA-mediated amino acid substitutions to…

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