Category: Human Brain
NIH’s ignorance: From roots to shoots (1)
NIH funded research on psychotherapeutic drugs failed to consider facts about how the light-activated assembly of the microRNA-RNA-peptide nanocomplex linked microRNA biogenesis in plants from…
The Darwin Code: Resurrected after 20 years (1)
See: Integrating high‐throughput microRNA and mRNA expression data to identify risk mRNA signature for pancreatic cancer prognosis 12/30/19 See also: Civil rights icon Rep. John…
mRNA Structure and Function (1)
See also: THE WORLD’S LARGEST MEETING TO ACCELERATE OLIGONUCLEOTIDE AND PEPTIDE PRODUCTS FROM EARLY DISCOVERY TO LATE-STAGE DEVELOPMENT & COMMERCIALIZATION May 11-20, 2020 The light-activated…
MicroRNAs on Veteran’s Day 2019
Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model 10/10/19 …the nasal-to-brain pathway is efficient and operable…
#SFN2019 to 2012: Hiding the facts (1)
From Fertilization to Adult Sexual Behavior (1996) Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to…
Chemogenetic kinetics (3): Psychopathology
Leucine–Histidine Dipeptide Attenuates Microglial Activation and Emotional Disturbances Induced by Brain Inflammation and Repeated Social Defeat Stress 9/9/19 …daily intake of these fermented foods is…
President Trump ends gun violence (1)
Pandemic and All-Hazards Preparedness and Advancing Innovation (PAHPAI) Act was signed into law by President Donald Trump in late June. The law addresses the prevention…
Bastardized health care (4)
California festival shooter claimed to be of Iranian and Italian descent 7/30/19 …he invited people to read “Might Is Right,” an 1890 book advocating for…
The tipping point (revisited): 87K (3)
My NCBI » Saved Search Settings “What’s new for ‘microRNA’ in PubMed”(5/29/19) 170 new items were added to the indexed articles in one day for…
Kohl and Francoeur at 25 (8)
Epigenetic Regulations in Neuropsychiatric Disorders (4/4/19) This article is part of the Research Topic: Genetics and Epigenetics of Psychiatric Diseases For a historical perspective on…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.