Category: Diseases & Disorders
Light and life-sucking black holes (3)
A universal trend of amino acid gain and loss in protein evolution (2/10/2005) Amino acid composition of proteins varies substantially between taxa and, thus, can…
Kohl and Francoeur at 25 (8)
Epigenetic Regulations in Neuropsychiatric Disorders (4/4/19) This article is part of the Research Topic: Genetics and Epigenetics of Psychiatric Diseases For a historical perspective on…
Light and life-sucking black holes (2)
Ethan Siegel may be the first to have responded, without attribution, to my claims in Light and life-sucking black holes (1) See: Could All Our…
Olfaction and microRNA signaling constrain longevity (4)
See: RNAi from Petunias to Worms (2006) Small RNAs can also be used to turn off large portions of the genome near centromeres via the…
Epic failure of the FDA: Gottlieb resigns (3)
From Epic failure of the FDA: Gottlieb resigns (2) I reiterate: The link from the anti-entropic virucidal energy of sunlight to naturally occurring RNA interference…
Olfaction and microRNA signaling constrain longevity (3)
Genetic compensation triggered by mutant mRNA degradation 4/3/19 Transcriptome analysis in alleles displaying mutant mRNA decay reveals the upregulation of a substantial proportion of the…
Olfaction and microRNA signaling constrain longevity (2)
Olfaction and microRNA signaling constrain longevity (1) 3/30/16 The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in…
Olfaction and microRNA signaling constrain longevity (1)
Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics…
Kohl and Francoeur at 25 (7)
MicroRNA Items: 1 to 20 of 84999 Feed-forward information and zero-lag synchronization in the sensory thalamocortical circuit are modulated during stimulus perception (3/25/19) …directional and…
Kohl and Francoeur at 25 (6)
Excerpt: Natural selection for energy-dependent codon optimality links what animals like to eat to biophysically constrained viral latency vira the physiology of their pheromone-controlled reproduction…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.