Posted in Adaptations Autophagy base editing biophotonics Cytosis MicroRNA biogenesis Pheromones Physics RNA interference Subatomic

79,000 reasons to believe in biophysical constraints

See also: 10,000 reasons to believe in biophysical constraints There once was a time when nobody knew how to do it. Now, anyone who fails…

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Posted in Adaptations Autophagy base editing biophotonics Cytosis MicroRNA biogenesis Model Organisms

CDC vs WHO (2): Adaptive regulatory variation

Summary: In their presentation from  the 2018 meeting of the American Society for Human Genetics, the Broad Institute, Jackson Laboratory, the Harvard University Department of…

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Posted in Adaptations Alternative Splicings Autophagy base editing Diseases & Disorders Ecology MicroRNA biogenesis Model Organisms

MicroRNA biogenesis protects us from HERVs (3)

endogenous: Biology growing or originating from within an organism. “endogenous gene sequences” Psychiatry (of a disease or symptom) not attributable to any external or environmental…

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Posted in Adaptations Alternative Splicings base editing biophotonics Cytosis Light Energy MicroRNA biogenesis

Creation of an enzyme that kills theories (4)

Conclusion: Don’t pretend that fixation of RNA-mediated amino acid substitutions is not all about energy-dependent changes in base pairs or you will be ridiculed. Creation…

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Posted in Adaptations Alternative Splicings Autophagy base editing Cytosis MicroRNA biogenesis Model Organisms

Copying Nature’s Design Process (1)

“What I do is copy nature’s design process.” October 3, 2013 (video 5:41 minutes) For 2018 Nobel Chemistry Prize Laureate Frances H. Arnold, evolution is…

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Posted in Adaptations base editing biophotonics MicroRNA biogenesis RNA-mediated epigenetic regulation of gene expression

The tipping point (revisited): 78,000 publications (3)

Structural basis of the nucleosome transition during RNA polymerase II passage Kujirai T, Ehara H, Fujino Y, Shirouzu M, Sekine S, Kurumizaka H Science (2018)…

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Please pardon me for figuratively continuing to jam examples like this down the throats of biologically uninformed theorists who are still touting ridiculous theories about mutation-driven evolution.
Posted in Adaptations Alternative Splicings base editing MicroRNA biogenesis RNA interference

The tipping point (revisited): 78,000 publications (1)

9/10/18 The tipping point (revisited): 77,000 publications (3)  See: MicroRNA  (I’m reporting in advance that in less than one month more than 1000 publications have…

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Posted in base editing Diseases & Disorders Light Energy MicroRNA biogenesis Subatomic

Epigenetic effects on so-called genetic endemism (3)

Ribosomes and cryo-EM: a duet …cryo-EM structures have revealed unprecedented insights into the function of ribosomes from a wide range of biological sources and in…

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Please pardon me for figuratively continuing to jam examples like this down the throats of biologically uninformed theorists who are still touting ridiculous theories about mutation-driven evolution.
Posted in Adaptations base editing MicroRNA biogenesis RNA-directed DNA methylation Uncategorized

Epigenetic effects on so-called genetic endemism (2)

I reiterate, “The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due…

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Please pardon me for figuratively continuing to jam examples like this down the throats of biologically uninformed theorists who are still touting ridiculous theories about mutation-driven evolution.
Posted in Adaptations Autophagy base editing Ecology MicroRNA biogenesis microRNA editing RNA interference

The microRNA-mediated brain-microbiome axis

Summary: TwitterBot for eQTL papers from PubMed, arXiv, bioRxiv, and PeerJ PrePrints (145 followers) and  Twitterbot for microRNA papers from PubMed, arXiv, bioRxiv, and PeerJ…

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