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Posted in Alternative Splicings Autophagy base editing biophotonics

The tipping point (revisited): 87K (2)

 Koel et al. (p. 976) show that major antigenic change can be caused by single amino acid substitutions. The antigenic changes have been linked to…

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The Traveling Wall
Posted in Adaptations Autophagy base editing biophotonics Chemogenetics Cytosis Diseases & Disorders Ecology

The tipping point (revisited): 87K (1)

A multicellular way of life for a multipartite virus (3/12/19) …the viral genome is not recapitulated in a single virus particle but in the viral…

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Posted in Adaptations Autophagy Diseases & Disorders Ecology Model Organisms Nutrigenomics Pheromones RNA interference What's in the News

Ecological Adaptations: From Angstroms to Ecosystems (2)

From the time I published my review of biophysically constrained nutritional epigenetics, which refuted the neo-Darwinian nonsense about mutation-driven evolution, 2834 more publications have mentioned…

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Posted in Adaptations Autophagy Cytosis Diseases & Disorders Ecology Light Energy Physics RNA interference Subatomic

Olfaction and microRNA signaling constrain longevity (2)

Olfaction and microRNA signaling constrain longevity (1) 3/30/16 The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in…

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Posted in Adaptations Autophagy Cytosis Diseases & Disorders Ecology Human Pheromones Model Organisms Subatomic

Olfaction and microRNA signaling constrain longevity (1)

Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics…

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Posted in Adaptations Alternative Splicings Autophagy base editing Cytosis Diseases & Disorders Ecology Light Energy microRNA editing Physics RNA editing RNA interference

Kohl and Francoeur at 25 (6)

Excerpt: Natural selection for energy-dependent codon optimality links what animals like to eat to biophysically constrained viral latency vira the physiology of their pheromone-controlled reproduction…

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Posted in Adaptations Autophagy Diseases & Disorders Ecology MicroRNA biogenesis microRNA editing Pheromones Variations

Epic failure of the FDA: Gottlieb resigns (2)

Epic failure of the FDA: Gottlieb resigns (1) We didn’t know it was possible for cells to survive crisis; we didn’t know autophagy is involved…

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Posted in Autophagy RNA interference

Epic failure of the FDA: Gottlieb resigns (1)

Autophagic cell death restricts chromosomal instability during replicative crisis 1/22/19 Our data suggest that autophagy is an integral component of the tumour suppressive crisis mechanism…

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Posted in Adaptations Autophagy Diseases & Disorders Ecology RNA interference RNA–Mediated Epigenetic Heredity

Biophysical constraints on RNA synthesis (1)

Includes: Constraints on amino acid substitutions in peptides Constraints on nanocomplexes Constraints on systems complexity Summary: The role that energy-dependent changes in the microRNA/messenger RNA…

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Posted in Adaptations Autophagy Cytosis Diseases & Disorders Ecology Subatomic

Preprints obfuscate facts (2)

See: Preprints obfuscate facts (1) See the preprint: Genetic dissection of assortative mating behavior 3/14/18 See also: PLOSBiology 2/7/19 Ecologically relevant mating cues (sometimes known…

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