Category: Autophagy
Olfaction and microRNA signaling constrain longevity (2)
Olfaction and microRNA signaling constrain longevity (1) 3/30/16 The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in…
Olfaction and microRNA signaling constrain longevity (1)
Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics…
Kohl and Francoeur at 25 (6)
Excerpt: Natural selection for energy-dependent codon optimality links what animals like to eat to biophysically constrained viral latency vira the physiology of their pheromone-controlled reproduction…
Epic failure of the FDA: Gottlieb resigns (2)
Epic failure of the FDA: Gottlieb resigns (1) We didn’t know it was possible for cells to survive crisis; we didn’t know autophagy is involved…
Epic failure of the FDA: Gottlieb resigns (1)
Autophagic cell death restricts chromosomal instability during replicative crisis 1/22/19 Our data suggest that autophagy is an integral component of the tumour suppressive crisis mechanism…
Biophysical constraints on RNA synthesis (1)
Includes: Constraints on amino acid substitutions in peptides Constraints on nanocomplexes Constraints on systems complexity Summary: The role that energy-dependent changes in the microRNA/messenger RNA…
Preprints obfuscate facts (2)
See: Preprints obfuscate facts (1) See the preprint: Genetic dissection of assortative mating behavior 3/14/18 See also: PLOSBiology 2/7/19 Ecologically relevant mating cues (sometimes known…
RNA processing and disease (4)
Genius Material Kills 99.9% of Bacteria in Drinking Water Using Nothing But Sunlight The authors linked the creation of virucidal light from the light-activated…
RNA processing and disease (3)
Evolution and the ice age 2/26/13 Scientists are discovering how the evolution of ecosystems has to be taken into account when speculating between different geological…
Blood music orchestrates human life (2)
From: Blood music orchestrates human life (1) The assessment of phylogenetic relationships that link the creation of sunlight and water to oxygen and microRNA biogenesis…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.