Category: Alternative Splicings
Light and life at base pair resolution (1)
Quantum Biosystems Raises ¥1B in Series C Financing Round …developing a single-molecule sequencing technology intended to significantly reduce the cost and improve the accuracy of…
Hide and seek with science facts (6)
Bernard Feringa: The Future of Chemistry – Schrödinger at 75: The Future of Biology (video) Levulan Kerastick and Blu-U link light-activated microRNA biogenesis in plants…
One mutation vs two amino acid substitutions
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission (2007) …a predominant human alpha-2,6 sialic acid binding preference is essential…
Hide and seek with science facts (2)
Largest Study of CRISPR-Cas9 Mutations Creates Prediction Tool for Gene Editing 11/28/18 (Lab Manager) CRISPR-Cas9 is an extremely important system for introducing mutations into DNA…
Hide and seek with science facts (3)
See also: Hide and seek with science facts (2) Despite CRISPR baby controversy, Harvard University will begin gene-editing sperm What if a new killer virus…
Hide and seek with science facts (4)
Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining They invented a new term to obfuscate facts about food energy-dependent RNA-mediated DNA repair….
MicroRNAs as therapeutic agents
Excerpt: See for comparison: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems (2018) Twitter is blocking my tweets when I include links to this open…
Kording lab refutes theistic evolution (2)
Kording lab refutes theistic evolution (1) Researchers from the Republic of South Korea have already linked light-actvated microRNA biogenesis to biophysically constrained viral latency and…
Kording lab refutes theistic evolution (1)
Conclusion: Attempts by biologically uninformed science journalists to pin down what is known about the links from ecological variation to ecological adaptation have caused Carl…
CSH perspectives: ignore the viral pandemic
The biochemical basis of microRNA targeting efficacy Posted September 11, 2018 as a bioRxiv preprint by David Bartel’s group. One feature that was not captured…
James V. Kohl detailedl how quantized energy-dependent microRNA biogenesis links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency and healthy longevity. Links from what organisms eat to the enzyme-dependent metabolism of food also link metabolic networks to microRNA-mediated genetic networks in the context of RNA interference. Drug therapies alter RNA interference by altering cell type differentiation in all cells of all individuals of all species. For comparison, during the past 26 years, Kohl has detailed how the chemistry of protein folding is biophysically constrained at every level of biological organization by conserved molecular mechanisms.