The ever increasing number of publications that link microRNA-mediated top down causation to prevention of virus-driven pathology attests to the facts from Biology could be so much more 11/22/19
…all that hard-earned expertise can get in the way. After all, nature isn’t neatly divided along disciplinary lines, so understanding it requires an integrated way of thinking. Put it this way: There’s a lot you can’t see when your eyes are glued to the microscope.
It’s a problem that Bruce S. McEwen often thinks about. A neuroendocrinology specialist and self-described nerd, he is wary of the fact that the more you become an expert on something, the more isolated you become.
Most specialists with their hard-earned expertise did not learn how to integrate what is known about the Creation of sunlight and water into a model of the oxygen-dependent prevention of DNA damage caused by nutrient-stress and social stress. That is why they failed to link stress to virus-driven physical and/or behavioral pathology.
Who are the experts who linked changes in behavior to facts about energy-dependent microRNA-mediated biophysical constraints?
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
Pseudoscientists do not want intelligent people to know that the ATP-dependent creation of RNA biophysically constrains viral latency and all pathology. The pseudoscientists prefer to obfuscate epigenetic cause and effect with claims about mutation-driven evolution and/or titles, such as this one.
The pseudoscientists know that most people will not look at the complexity of top-down energy-dependent biophysically constrained Creation of cell type differences in the context of articles like this one:
MicroRNAs (miRNAs) as the regulatory short noncoding RNAs are involved in a wide array of cellular and molecular processes.
…act as oncomirs or tumor suppressors …involved in cell proliferation, apoptosis, autophagy, angiogenesis…exert their regulatory effects through modulating multiple signaling pathways…
All the signalling pathways are also linked to drug resistance, which is a Big Pharma nightmare. Drug development virtually stalled when facts about naturally occurring light-activated carbon fixation were linked to biophysically constrained RNA interference in this patent for the prevention of all virus-driven pathology.
5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).
Pseudoscientists prefer to place their claims about viruses into the context of inferences in articles like this one.
Serious scientists reject the inferences of pseudoscientists and continue to contribute experimental evidence of biophysically constrained cause and effect.
…miRNAs that could modulate immunopathogenesis are discussed. Major hurdles lie in the development of chemical modifications and delivery systems for in vivo delivery. Nevertheless, advancement in miRNA formulations and delivery systems hold great promise for the therapeutic potential of miRNA-based therapy…
I have repeatedly mentioned that the energy-dependent microRNA-mediated cure for all cancers was patented on 12/25/18. See: Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest and see their Proof of concept
The proof of concept links their creation of energy-dependent peptides to prevention of cancers caused by the virus-driven degradation of messenger RNA, which links the creation of toxic peptides to all pathology.
The only hope that serious scientists may prevail against the pseudoscientific nonsense, which obfuscates cause and effect, comes from those who know how to link what organisms eat the the stability of organized genomes across kingdoms.
See also: Precision Medicine Approaches to Prevent Gastric Cancer 1/6/20
If it is not yet obvious to you that all serious scientists will continue to refute the nonsense touted by neo-Darwinian theorists and Big Bang cosmologists, you need only search for more indexed published works that mention the term “microRNA” for comparison to those that ignore more than 96,000 already published works linked to sympatric speciation across kingdoms via the Creation of sunlight, water, and oxidative phosphorylation.
The epic failure of genome-wide association studies (GWAS) to unravel facts about energy-dependent gene expression, microRNA-mediated proteomics, and biophysically constrained metabolomics has failed to link numerous pathophysiological pathways to complex disorders and generated only many more useless hypotheses that cannot be linked to the functional structure of supercoiled DNA via oxidative phosphorylation, which protects organized genomes from virus-driven pathology.