Bottom-up biology (revisited)

See first: Bottom up biology

Summary: Serious scientists have linked UV light-activated gene expression and the cascade of base editing, microRNA editing and RNA editing to energy-dependent fixation of amino acid substitutions and species-specific cell type differentiation via the physiology of pheromone-controlled biophysically constrained viral latency.

See also: MicroRNAs buffer genetic variation at specific temperatures during embryonic development

The light-activated creation of microRNAs links energy-dependent constraints on viral latency to healthy longevity.  Virus-driven energy theft links the degradation of messenger RNA from mutations to all pathology. Link that historical perspective to the cooperation among God-less Communists (North Korea) and scientific creationists (Republic of Korea).

Scientific creationists in the Republic of Korea, Israel, and other countries know how endogenous retroviruses are biophysically constrained, and what happens in the context of contraint-breaking mutations.

Research reveals details of how HIV becomes infectious 11/13/18

“Old World monkeys [such as rhesus monkeys] have TRIM5-alpha, and in those primates, it stops the HIV infection,” Polenova said. “Humans have the same protein, with some primary amino acid sequence differences, but in humans, it doesn’t disrupt the capsid and it doesn’t stop the infection.”

The EDAR V370A variant in Old World and New World populations of humans links one amino acid sequence difference to morphological and behavioral traits via the mouse-to-human model of food energy-dependent pheromone-controlled reproduction and biophysically constrained viral latency in species from microbes to humans.

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk

The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection…

Biologically uninformed theorists have linked these bouts of positive selection to the evolution of all nutrient-dependent pheromone-controlled biodiversity in species from microbes to humans.

For comparison, see also: Promises and Challenges in Continuous Tracking Utilizing Amino Acids in Skin Secretions for Active Multi-Factor Biometric Authentication for Cybersecurity

Figure 1. Biocatalytic cascade for optical detection of three amino acids, using two detection pathways: A) measurement of NADH at 340 nm, and B) conversion of NADH to a visible color

Serious scientists have linked UV light-activated gene expression and the cascade of base editing, microRNA editing and RNA editing to energy-dependent fixation of amino acid substitutions and species-specific cell type differentiation via the physiology of pheromone-controlled biophysically constrained viral latency.

The spectacular visualizations of energy-dependent changes can now be viewed in the context of the cryo-EM technology, which can be linked to the visualization of brain development in this “scientific art.”

See also: Cloning of Autophagy-Related MicroRNAs

MicroRNAs were introduced as novel regulators of autophagy, and accumulating results underlined the fact that they constituted an important layer of biological control mechanism on the autophagic activity.

Image may contain: 1 person

Clock towers and other vantage points have repeatedly been linked from amino acid substitutions in mentally deranged shooters to the preventable deaths of many people.

During the 2014 SFN poster session previews, McCann and Huhman and Zinzow-Kramer et al., linked the pheromone-controlled social regulation of COMT Val158Met to the prevention of school shootings and other gun violence.

See also: Social defeat induces changes in histone acetylation and expression of histone modifying enzymes in the ventral hippocampus, prefrontal cortex, and dorsal raphe nucleus (4/14/14)

If you ignore the concept of global maxima and biophysically constrained global minima, your mathematical models may make sense. If you start with the creation of sunlight, you may be or become a serious scientist.

Here’s an example of how others have tried to lead the way. Virus-mediated archaeal hecatomb in the deep seafloor

I asked Kevin J. Mitchell:

What will you say when intelligent people ask about the two recent reports that link food energy-dependent RNA interference to pheromone-controlled viral latency and healthy longevity?

1) Three vital RNA functions and interactions in the process of silk gland apoptosis in silkworm Bombyx mori

2) The odour of human milk: Its chemical variability and detection by newborns

See also: Feedback Loops Link Odor and Pheromone Signaling with Reproduction

What will biologically uninformed pseudoscientists and other theorists tell people whose loved ones have been killed by school shooters or by other gun violence, when intelligent people learn that prevention may require only the readily available check for variants of COMT Val158Met?

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Author: James Kohl

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